FNab09940

antibody from FineTest Biotech

Targeting: HIF1A bHLHe78, HIF-1alpha, HIF1, MOP1, PASD8

Western blot

ELISA

Immunocytochemistry

Antibody data

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Validation data

Product number: FNab09940 - Provider product page
Provider: FineTest Biotech
Product name: HIF1a antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: Under normal oxygen conditions, HIF1a is continuously produced and destroyed, in a process involving hydroxylation, interaction with von Hippel-Lindau (VHL) protein, polyubiquitylation and subsequent proteasomal degradation. Under hypoxic conditions, hydroxylation is impaired and HIF1a is stabilized. HIF1a localizes in cytoplasm in normoxia, but it can translocate into nuclear in response to hypoxia. The calculated molecular weight of HIF1a is 93 kDa, but the modified protein HIF1a is about 110-120kDa (PMID: 11698256, .PMID: 7539918).
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: hypoxia inducible factor 1, alpha s ubunit(basic helix-loop-helix trans cription factor)
Epitope: IgG1
Isotype: IgG
Antibody clone number: 5H12
Vial size: 100¦Ìg
Concentration: protein A+G purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

HIF1A protein structure - FNab09940 shown in red.