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- Antibody Data
- Antigen structure
- References [39]
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- Validations
- Western blot [3]
- Immunohistochemistry [1]
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- Product number
- 18933-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18933-1-AP, RRID:AB_10641999
- Product name
- BMP2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated BMP2 antibody (Cat. #18933-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Role of Nox4 in High Calcium-Induced Renal Oxidative Stress Damage and Crystal Deposition.
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects.
Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway.
Cigarette smoke induced neural tube defects by down-regulating noggin expression.
BMP2 induces hMSC osteogenesis and matrix remodeling.
Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging.
The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway.
Experimental study of expression profile and specific role of human microRNAs in regulating atrophic bone nonunion.
Schisandrin B regulates MC3T3-E1 subclone 14 cells proliferation and differentiation through BMP2-SMADs-RUNX2-SP7 signaling axis.
The role of WNT1 mutant variant (WNT1c.677C>T ) in osteogenesis imperfecta.
Osteoking improves OP rat by enhancing HSP90‑β expression.
Expression and distribution of bone morphogenetic protein 4 and its antagonist Noggin in the skin of Kazakh sheep (Ovis aries) with a white and brown coat color.
SHED-derived conditioned exosomes enhance the osteogenic differentiation of PDLSCs via Wnt and BMP signaling in vitro.
Noggin Inhibits IL-1β and BMP-2 Expression, and Attenuates Cartilage Degeneration and Subchondral Bone Destruction in Experimental Osteoarthritis.
Exosomes derived from miR-375-overexpressing human adipose mesenchymal stem cells promote bone regeneration.
Loss of Fam20c causes defects in the acinar and duct structure of salivary glands in mice.
ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis.
Oviductus Ranae protein hydrolyzate prevents menopausal osteoporosis by regulating TGFβ/BMP2 signaling.
Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway.
Specific knockdown of WNT8b expression protects against phosphate-induced calcification in vascular smooth muscle cells by inhibiting the Wnt-β-catenin signaling pathway.
Sp1 Plays an Important Role in Vascular Calcification Both In Vivo and In Vitro.
Bacitracin promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by stimulating the bone morphogenetic protein-2/Smad axis.
Negative pressure wound therapy promotes muscle-derived stem cell osteogenic differentiation through MAPK pathway.
Icariin attenuates titanium particle-induced inhibition of osteogenic differentiation and matrix mineralization via miR-21-5p.
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.
Targeted silencing of SOX2 by an artificial transcription factor showed antitumor effect in lung and esophageal squamous cell carcinoma.
Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis.
Promotive effects of bone morphogenetic protein 2 on angiogenesis in hepatocarcinoma via multiple signal pathways.
Metformin alleviates vascular calcification induced by vitamin D3 plus nicotine in rats via the AMPK pathway.
A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4.
Dynamic cultivation with radial flow bioreactor enhances proliferation or differentiation of rat bone marrow cells by fibroblast growth factor or osteogenic differentiation factor.
Guided bone regeneration is promoted by the molecular events in the membrane compartment.
Hypoxia-induced MTA1 promotes MC3T3 osteoblast growth but suppresses MC3T3 osteoblast differentiation.
Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.
Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve.
Effects of sodium fluoride treatment in vitro on cell proliferation, BMP-2 and BMP-3 expression in human osteosarcoma MG-63 cells.
Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses.
Regulation of Olig2 during astroglial differentiation in the subventricular zone of a cuprizone-induced demyelination mouse model.
Construction of a eukaryotic expression vector pEGFP-C1-BMP-2 and its effect on cell migration.
Xun Y, Zhou P, Yang Y, Li C, Zhang J, Hu H, Qin B, Zhang Z, Wang Q, Lu Y, Wang S
Antioxidants & redox signaling 2021 Nov 25;
Antioxidants & redox signaling 2021 Nov 25;
Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects.
Ma WQ, Sun XJ, Zhu Y, Liu NF
Free radical biology & medicine 2021 Mar;165:229-242
Free radical biology & medicine 2021 Mar;165:229-242
Effects of WNT1 c.110 T>C and c.505G>T mutations on osteoblast differentiation via the WNT1/β-catenin signaling pathway.
Zhang B, Li R, Wang W, Zhou X, Luo B, Zhu Z, Zhang X, Ding A
Journal of orthopaedic surgery and research 2021 Jun 2;16(1):359
Journal of orthopaedic surgery and research 2021 Jun 2;16(1):359
Cigarette smoke induced neural tube defects by down-regulating noggin expression.
Yin C, Cai H, Yang D, Jian Y, Zhang J, Li Z, Wang D
Birth defects research 2021 Jan 1;113(1):5-13
Birth defects research 2021 Jan 1;113(1):5-13
BMP2 induces hMSC osteogenesis and matrix remodeling.
Cai H, Zou J, Wang W, Yang A
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Higher BMP Expression in Tendon Stem/Progenitor Cells Contributes to the Increased Heterotopic Ossification in Achilles Tendon With Aging.
Dai G, Li Y, Liu J, Zhang C, Chen M, Lu P, Rui Y
Frontiers in cell and developmental biology 2020;8:570605
Frontiers in cell and developmental biology 2020;8:570605
The Role of Tantalum Nanoparticles in Bone Regeneration Involves the BMP2/Smad4/Runx2 Signaling Pathway.
Zhang G, Liu W, Wang R, Zhang Y, Chen L, Chen A, Luo H, Zhong H, Shao L
International journal of nanomedicine 2020;15:2419-2435
International journal of nanomedicine 2020;15:2419-2435
Experimental study of expression profile and specific role of human microRNAs in regulating atrophic bone nonunion.
Wei J, Chen H, Fu Y, Zhang B, Zhang L, Tao S, Lin F
Medicine 2020 Sep 4;99(36):e21653
Medicine 2020 Sep 4;99(36):e21653
Schisandrin B regulates MC3T3-E1 subclone 14 cells proliferation and differentiation through BMP2-SMADs-RUNX2-SP7 signaling axis.
Wang X, Liao X, Zhang Y, Wei L, Pang Y
Scientific reports 2020 Sep 2;10(1):14476
Scientific reports 2020 Sep 2;10(1):14476
The role of WNT1 mutant variant (WNT1c.677C>T ) in osteogenesis imperfecta.
Zhang B, Li R, Wang W, Zhou X, Luo B, Zhu Z, Zhang X, Ding A
Annals of human genetics 2020 Nov;84(6):447-455
Annals of human genetics 2020 Nov;84(6):447-455
Osteoking improves OP rat by enhancing HSP90‑β expression.
Sun Y, Chen R, Zhu D, Shen ZQ, Zhao HB, Lee WH
International journal of molecular medicine 2020 May;45(5):1543-1553
International journal of molecular medicine 2020 May;45(5):1543-1553
Expression and distribution of bone morphogenetic protein 4 and its antagonist Noggin in the skin of Kazakh sheep (Ovis aries) with a white and brown coat color.
Sun X, Qu G, Wang D, Wang T, Sai W, Chen Y, Yuan L, Pang Q
Acta histochemica 2020 May;122(4):151539
Acta histochemica 2020 May;122(4):151539
SHED-derived conditioned exosomes enhance the osteogenic differentiation of PDLSCs via Wnt and BMP signaling in vitro.
Wang M, Li J, Ye Y, He S, Song J
Differentiation; research in biological diversity 2020 Jan - Feb;111:1-11
Differentiation; research in biological diversity 2020 Jan - Feb;111:1-11
Noggin Inhibits IL-1β and BMP-2 Expression, and Attenuates Cartilage Degeneration and Subchondral Bone Destruction in Experimental Osteoarthritis.
Chien SY, Tsai CH, Liu SC, Huang CC, Lin TH, Yang YZ, Tang CH
Cells 2020 Apr 10;9(4)
Cells 2020 Apr 10;9(4)
Exosomes derived from miR-375-overexpressing human adipose mesenchymal stem cells promote bone regeneration.
Chen S, Tang Y, Liu Y, Zhang P, Lv L, Zhang X, Jia L, Zhou Y
Cell proliferation 2019 Sep;52(5):e12669
Cell proliferation 2019 Sep;52(5):e12669
Loss of Fam20c causes defects in the acinar and duct structure of salivary glands in mice.
Miao N, Zhan Y, Xu Y, Yuan H, Qin C, Lin F, Xie X, Mu S, Yuan M, Mu H, Guo S, Li Y, Zhang B
International journal of molecular medicine 2019 May;43(5):2103-2117
International journal of molecular medicine 2019 May;43(5):2103-2117
ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis.
Ge L, Cui Y, Liu B, Yin X, Pang J, Han J
Molecular medicine reports 2019 May;19(5):3469-3476
Molecular medicine reports 2019 May;19(5):3469-3476
Oviductus Ranae protein hydrolyzate prevents menopausal osteoporosis by regulating TGFβ/BMP2 signaling.
Li X, Sui X, Yang Q, Li Y, Li N, Shi X, Han D, Li Y, Huang X, Yu P, Qu X
Archives of gynecology and obstetrics 2019 Mar;299(3):873-882
Archives of gynecology and obstetrics 2019 Mar;299(3):873-882
Mmu-miR-185 depletion promotes osteogenic differentiation and suppresses bone loss in osteoporosis through the Bgn-mediated BMP/Smad pathway.
Cui Q, Xing J, Yu M, Wang Y, Xu J, Gu Y, Nan X, Ma W, Liu H, Zhao H
Cell death & disease 2019 Feb 20;10(3):172
Cell death & disease 2019 Feb 20;10(3):172
Specific knockdown of WNT8b expression protects against phosphate-induced calcification in vascular smooth muscle cells by inhibiting the Wnt-β-catenin signaling pathway.
Tian BY, Yao L, Sheng ZT, Wan PZ, Qiu XB, Wang J, Xu TH
Journal of cellular physiology 2019 Apr;234(4):3469-3477
Journal of cellular physiology 2019 Apr;234(4):3469-3477
Sp1 Plays an Important Role in Vascular Calcification Both In Vivo and In Vitro.
Zhang X, Li R, Qin X, Wang L, Xiao J, Song Y, Sheng X, Guo M, Ji X
Journal of the American Heart Association 2018 Mar 23;7(6)
Journal of the American Heart Association 2018 Mar 23;7(6)
Bacitracin promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by stimulating the bone morphogenetic protein-2/Smad axis.
Li H, Nie B, Du Z, Zhang S, Long T, Yue B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:588-597
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:588-597
Negative pressure wound therapy promotes muscle-derived stem cell osteogenic differentiation through MAPK pathway.
Liu H, Zheng X, Chen L, Jian C, Hu X, Zhao Y, Li Z, Yu A
Journal of cellular and molecular medicine 2018 Jan;22(1):511-520
Journal of cellular and molecular medicine 2018 Jan;22(1):511-520
Icariin attenuates titanium particle-induced inhibition of osteogenic differentiation and matrix mineralization via miR-21-5p.
Lian F, Zhao C, Qu J, Lian Y, Cui Y, Shan L, Yan J
Cell biology international 2018 Aug;42(8):931-939
Cell biology international 2018 Aug;42(8):931-939
Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway.
Fan S, Gao X, Chen P, Li X
Life sciences 2018 Aug 15;207:205-211
Life sciences 2018 Aug 15;207:205-211
Targeted silencing of SOX2 by an artificial transcription factor showed antitumor effect in lung and esophageal squamous cell carcinoma.
Yokota E, Yamatsuji T, Takaoka M, Haisa M, Takigawa N, Miyake N, Ikeda T, Mori T, Ohno S, Sera T, Fukazawa T, Naomoto Y
Oncotarget 2017 Nov 28;8(61):103063-103076
Oncotarget 2017 Nov 28;8(61):103063-103076
Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis.
Sun J, Liu X, Gao H, Zhang L, Ji Q, Wang Z, Zhou L, Wang Y, Sui H, Fan Z, Li Q
Oncotarget 2017 Feb 14;8(7):11489-11506
Oncotarget 2017 Feb 14;8(7):11489-11506
Promotive effects of bone morphogenetic protein 2 on angiogenesis in hepatocarcinoma via multiple signal pathways.
Zuo WH, Zeng P, Chen X, Lu YJ, Li A, Wu JB
Scientific reports 2016 Nov 25;6:37499
Scientific reports 2016 Nov 25;6:37499
Metformin alleviates vascular calcification induced by vitamin D3 plus nicotine in rats via the AMPK pathway.
Zhang X, Xiao J, Li R, Qin X, Wang F, Mao Y, Liang W, Sheng X, Guo M, Song Y, Ji X
Vascular pharmacology 2016 Jun;81:83-90
Vascular pharmacology 2016 Jun;81:83-90
A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4.
Wang W, Chen H, Zhang L, Qin Y, Cong Q, Wang P, Ding K
Carbohydrate polymers 2016 Jun 25;144:305-14
Carbohydrate polymers 2016 Jun 25;144:305-14
Dynamic cultivation with radial flow bioreactor enhances proliferation or differentiation of rat bone marrow cells by fibroblast growth factor or osteogenic differentiation factor.
Kanda Y, Nishimura I, Sato T, Katayama A, Arano T, Ikada Y, Yoshinari M
Regenerative therapy 2016 Dec;5:17-24
Regenerative therapy 2016 Dec;5:17-24
Guided bone regeneration is promoted by the molecular events in the membrane compartment.
Turri A, Elgali I, Vazirisani F, Johansson A, Emanuelsson L, Dahlin C, Thomsen P, Omar O
Biomaterials 2016 Apr;84:167-183
Biomaterials 2016 Apr;84:167-183
Hypoxia-induced MTA1 promotes MC3T3 osteoblast growth but suppresses MC3T3 osteoblast differentiation.
Liu T, Zou W, Shi G, Xu J, Zhang F, Xiao J, Wang Y
European journal of medical research 2015 Feb 3;20:10
European journal of medical research 2015 Feb 3;20:10
Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.
Zhou Y, Wang JY, Feng H, Wang C, Li L, Wu D, Lei H, Li H, Wu LL
Arteriosclerosis, thrombosis, and vascular biology 2014 May;34(5):1002-10
Arteriosclerosis, thrombosis, and vascular biology 2014 May;34(5):1002-10
Role of Wnt/β-catenin signaling pathway in the mechanism of calcification of aortic valve.
Gu GJ, Chen T, Zhou HM, Sun KX, Li J
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Feb;34(1):33-36
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Feb;34(1):33-36
Effects of sodium fluoride treatment in vitro on cell proliferation, BMP-2 and BMP-3 expression in human osteosarcoma MG-63 cells.
Wei Y, Wu Y, Zeng B, Zhang H
Biological trace element research 2014 Dec;162(1-3):18-25
Biological trace element research 2014 Dec;162(1-3):18-25
Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses.
Xu D, Yang W, Hu Y, Luo Z, Li J, Hou Y, Liu Y, Cai K
Colloids and surfaces. B, Biointerfaces 2013 Oct 1;110:225-35
Colloids and surfaces. B, Biointerfaces 2013 Oct 1;110:225-35
Regulation of Olig2 during astroglial differentiation in the subventricular zone of a cuprizone-induced demyelination mouse model.
Chen LP, Li ZF, Ping M, Li R, Liu J, Xie XH, Song XJ, Guo L
Neuroscience 2012 Sep 27;221:96-107
Neuroscience 2012 Sep 27;221:96-107
Construction of a eukaryotic expression vector pEGFP-C1-BMP-2 and its effect on cell migration.
Wang XY, Chen ZH, Zhang RY, Liu SQ, Mei Z, Yu YY, Zhang X, Xia Q, Ding YM
Journal of Zhejiang University. Science. B 2012 May;13(5):356-63
Journal of Zhejiang University. Science. B 2012 May;13(5):356-63
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 18933-1-AP(BMP2 antibody) at dilution of 1:1000
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HT-1080 cells were subjected to SDS PAGE followed by western blot with 18933-1-AP(BMP2 antibody) at dilution of 1:1000
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Sp2/0 cells were subjected to SDS PAGE followed by western blot with 18933-1-AP(BMP2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The BMP2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human BMP2. This antibody recognizes human,mouse,rat,pig antigen. The BMP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
