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- Product number
- ABIN394132 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Stem-Loop Binding Protein (SLBP) (AA 1-271) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-271
- Isotype
- IgG
- Antibody clone number
- 2C4-1C8
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Knockdown of SLBP results in nuclear retention of histone mRNA.
Phosphorylation of threonine 61 by cyclin a/Cdk1 triggers degradation of stem-loop binding protein at the end of S phase.
Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.
SLIP1, a factor required for activation of histone mRNA translation by the stem-loop binding protein.
NELF interacts with CBC and participates in 3' end processing of replication-dependent histone mRNAs.
Sullivan KD, Mullen TE, Marzluff WF, Wagner EJ
RNA (New York, N.Y.) 2009 Mar;15(3):459-72
RNA (New York, N.Y.) 2009 Mar;15(3):459-72
Phosphorylation of threonine 61 by cyclin a/Cdk1 triggers degradation of stem-loop binding protein at the end of S phase.
Koseoglu MM, Graves LM, Marzluff WF
Molecular and cellular biology 2008 Jul;28(14):4469-79
Molecular and cellular biology 2008 Jul;28(14):4469-79
Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'.
Mullen TE, Marzluff WF
Genes & development 2008 Jan 1;22(1):50-65
Genes & development 2008 Jan 1;22(1):50-65
SLIP1, a factor required for activation of histone mRNA translation by the stem-loop binding protein.
Cakmakci NG, Lerner RS, Wagner EJ, Zheng L, Marzluff WF
Molecular and cellular biology 2008 Feb;28(3):1182-94
Molecular and cellular biology 2008 Feb;28(3):1182-94
NELF interacts with CBC and participates in 3' end processing of replication-dependent histone mRNAs.
Narita T, Yung TM, Yamamoto J, Tsuboi Y, Tanabe H, Tanaka K, Yamaguchi Y, Handa H
Molecular cell 2007 May 11;26(3):349-65
Molecular cell 2007 May 11;26(3):349-65
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- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
