Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60269 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- AZGP1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human AZGP1.
- Description
- ZAG (Zn-a2-glycoprotein, also designated Zn-a2-gp) is a soluble, secreted protein found in serum and other body fluids (such as cerebrospinal fluid, blood plasma, urine and sweat). ZAG has a tendency to precipitate with zinc salts, has electrophoretic mobility in the region of the two globulins, and has 18% carbohydrate content. A member of the immunoglobulin superfamily, ZAG has a high degree of sequence similarity to class-I major histocompatibility complex (MHC) antigens. The ZAG structure includes a large groove analogous to class I MHC peptide binding grooves. The crystal structure of ZAG resembles a class I MHC heavy chain but does not bind the class I light chain b-2-Microglobulin, unlike other MHC related proteins. ZAG stimulates lipid degradation in adipocytes and its overexpression causes the extensive fat losses associated with some advanced cancers.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of AZGP1 pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:Mouse heart tissue lysateLane3:Rat heart tissue lysate