Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN2838594 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3) (AA 1-101) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Rat
- Host
- Mouse
- Epitope
- AA 1-101
- Isotype
- IgG
- Antibody clone number
- 6C4
- Vial size
- 50 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Transforming acidic coiled-coil-containing protein 3 (TACC3) overexpression in hepatocellular carcinomas is associated with "stemness" and epithelial-mesenchymal transition-related marker expression and a poor prognosis.
Centrosome-related genes, genetic variation, and risk of breast cancer.
A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer.
Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.
Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.
Cdh1 controls the stability of TACC3.
Nahm JH, Kim H, Lee H, Cho JY, Choi YR, Yoon YS, Han HS, Park YN
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):393-403
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):393-403
Centrosome-related genes, genetic variation, and risk of breast cancer.
Olson JE, Wang X, Pankratz VS, Fredericksen ZS, Vachon CM, Vierkant RA, Cerhan JR, Couch FJ
Breast cancer research and treatment 2011 Jan;125(1):221-8
Breast cancer research and treatment 2011 Jan;125(1):221-8
A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer.
Kiemeney LA, Sulem P, Besenbacher S, Vermeulen SH, Sigurdsson A, Thorleifsson G, Gudbjartsson DF, Stacey SN, Gudmundsson J, Zanon C, Kostic J, Masson G, Bjarnason H, Palsson ST, Skarphedinsson OB, Gudjonsson SA, Witjes JA, Grotenhuis AJ, Verhaegh GW, Bishop DT, Sak SC, Choudhury A, Elliott F, Barrett JH, Hurst CD, de Verdier PJ, Ryk C, Rudnai P, Gurzau E, Koppova K, Vineis P, Polidoro S, Guarrera S, Sacerdote C, Campagna M, Placidi D, Arici C, Zeegers MP, Kellen E, Gutierrez BS, Sanz-Velez JI, Sanchez-Zalabardo M, Valdivia G, Garcia-Prats MD, Hengstler JG, Blaszkewicz M, Dietrich H, Ophoff RA, van den Berg LH, Alexiusdottir K, Kristjansson K, Geirsson G, Nikulasson S, Petursdottir V, Kong A, Thorgeirsson T, Mungan NA, Lindblom A, van Es MA, Porru S, Buntinx F, Golka K, Mayordomo JI, Kumar R, Matullo G, Steineck G, Kiltie AE, Aben KK, Jonsson E, Thorsteinsdottir U, Knowles MA, Rafnar T, Stefansson K
Nature genetics 2010 May;42(5):415-9
Nature genetics 2010 May;42(5):415-9
Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.
Lin CH, Hu CK, Shih HM
The Journal of cell biology 2010 Jun 28;189(7):1097-105
The Journal of cell biology 2010 Jun 28;189(7):1097-105
Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.
Couch FJ, Wang X, Bamlet WR, de Andrade M, Petersen GM, McWilliams RR
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010 Jan;19(1):251-7
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010 Jan;19(1):251-7
Cdh1 controls the stability of TACC3.
Jeng JC, Lin YM, Lin CH, Shih HM
Cell cycle (Georgetown, Tex.) 2009 Nov 1;8(21):3537-44
Cell cycle (Georgetown, Tex.) 2009 Nov 1;8(21):3537-44
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Supportive validation
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC