BS6710

antibody from Bioworld Technology, Inc
Targeting: PROS1 PROS
Provider product page for BS6710
Western blot
Immunohistochemistry

Antibody data

Product number
BS6710 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PROS1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PROS1.
Description
Protein S (PROS) is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated protein C (APC) and facilitates clearance of early apoptotic cells. In the plasma, circulating Protein S becomes inactive upon complexing with C4b-binding protein (C4BP); 60-70% of Protein S circulates in complex with C4BP. Calcium-dependent association of C4BP-Protein S with apoptotic cells influences the regulation of complement activation. Protein S has APC-independent anticoagulant activity through direct inhibition of prothrombin activation via interactions with Factor X A, Factor V A and phospholipids. Autosomal dominant Protein S deficiency (levels 15 to 37% of normal) correlates with severe recurrent venous thrombosis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PROS1 protein structure - BS6710 shown in red.