FNab00341

antibody from FineTest Biotech

Targeting: A2M CPAMD5, FWP007, S863-7

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

FNab00341

Provider

FineTest Biotech

Product name

Alpha-2-macroglobulin antibody

Antibody type

Monoclonal

Antigen

Recombinant protein fragment

Description

Alpha-2-macroglobulin, also known as ¦Á2-macroglobulin(¦Á2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer¡¯s disease.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Antigen sequence

alpha-2-macroglobulin


Epitope

IgG2a

Isotype

IgG

Antibody clone number

6D0

Vial size

100¦Ìg

Concentration

Protein A+G purification

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

Handling

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)