Antibody data
- Antibody Data
- Antigen structure
- References [51]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 21327-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21327-1-AP, RRID:AB_10733646
- Product name
- Cathepsin D antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Cathepsin D antibody (Cat. #21327-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cyclic helix B peptide promotes random-pattern skin flap survival via TFE3-mediated enhancement of autophagy and reduction of ROS levels.
Epigenetic regulator BRD4 is involved in cadmium-induced acute kidney injury via contributing to lysosomal dysfunction, autophagy blockade and oxidative stress.
GDF-11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3-Mediated Autophagy Augmentation.
Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps.
Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway.
Curcumin promotes the survival of ischemic random skin flaps via autophagy.
Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Prenatal-onset of congenital neuronal ceroid lipofuscinosis with a novel CTSD mutation.
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Exenatide improves random-pattern skin flap survival via TFE3 mediated autophagy augment.
Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons.
Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective.
Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson's disease models.
Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD.
Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis.
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
DDRGK1, a crucial player of ufmylation system, is indispensable for autophagic degradation by regulating lysosomal function.
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Hydroxysafflor yellow A promotes multiterritory perforating flap survival: an experimental study.
Detrimental Effect of Sitagliptin Induced Autophagy on Multiterritory Perforator Flap Survival.
Staphylococcus aureus Avoids Autophagy Clearance of Bovine Mammary Epithelial Cells by Impairing Lysosomal Function.
Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Survival.
Notoginsenoside R1 Protects Against the Acrylamide-Induced Neurotoxicity via Upregulating Trx-1-Mediated ITGAV Expression: Involvement of Autophagy.
Baicalein Attenuates Pyroptosis and Endoplasmic Reticulum Stress Following Spinal Cord Ischemia-Reperfusion Injury via Autophagy Enhancement.
TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress.
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway.
Autophagic blockage by bismuth sulfide nanoparticles inhibits migration and invasion of HepG2 cells.
Heat shock factor 4 regulates lysosome activity by modulating the αB-crystallin-ATP6V1A-mTOR complex in ocular lens.
An Experimental Model of Neurodegenerative Disease Based on Porcine Hemagglutinating Encephalomyelitis Virus-Related Lysosomal Abnormalities.
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Combined toxic effects of CBNPs and Pb on rat alveolar macrophage apoptosis and autophagy flux.
Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting.
27-Hydroxycholesterol Contributes to Lysosomal Membrane Permeabilization-Mediated Pyroptosis in Co-cultured SH-SY5Y Cells and C6 Cells.
Protective effects of resveratrol on random-pattern skin flap survival: an experimental study.
Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy.
FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
ERβ promotes Aβ degradation via the modulation of autophagy.
Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy.
NDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy.
Green Tea Polyphenols, Mimicking the Effects of Dietary Restriction, Ameliorate High-Fat Diet-Induced Kidney Injury via Regulating Autophagy Flux.
TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation.
Epigallocatechin-3-gallate inhibits H2O2-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.
Tetrandrine is a potent cell autophagy agonist via activated intracellular reactive oxygen species.
Synergistic anti-tumour effects of tetrandrine and chloroquine combination therapy in human cancer: a potential antagonistic role for p21.
Citreoviridin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis in Human Liver HepG2 Cells.
Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells.
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway.
Proteomic features of potential tumor suppressor NESG1 in nasopharyngeal carcinoma.
Lou J, Zhang H, Qi J, Xu Y, Wang X, Jiang J, Hu X, Ni L, Cai Y, Wang X, Gao W, Xiao J, Zhou K
British journal of pharmacology 2022 Jan;179(2):301-321
British journal of pharmacology 2022 Jan;179(2):301-321
Epigenetic regulator BRD4 is involved in cadmium-induced acute kidney injury via contributing to lysosomal dysfunction, autophagy blockade and oxidative stress.
Gong ZG, Zhao Y, Wang ZY, Fan RF, Liu ZP, Wang L
Journal of hazardous materials 2022 Feb 5;423(Pt A):127110
Journal of hazardous materials 2022 Feb 5;423(Pt A):127110
GDF-11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3-Mediated Autophagy Augmentation.
Xu Y, Hu X, Li F, Zhang H, Lou J, Wang X, Wang H, Yin L, Ni W, Kong J, Wang X, Li Y, Zhou K, Xu H
Oxidative medicine and cellular longevity 2021;2021:8186877
Oxidative medicine and cellular longevity 2021;2021:8186877
Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps.
Zhu X, Hu X, Lou J, Li J, Xu Y, Yu G, Wu C, Ding J, Gao W, Xiao J, Zhou K, Jia C
Oxidative medicine and cellular longevity 2021;2021:6610603
Oxidative medicine and cellular longevity 2021;2021:6610603
Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway.
Wu C, Chen H, Zhuang R, Zhang H, Wang Y, Hu X, Xu Y, Li J, Li Y, Wang X, Xu H, Ni W, Zhou K
International journal of biological sciences 2021;17(4):1138-1152
International journal of biological sciences 2021;17(4):1138-1152
Curcumin promotes the survival of ischemic random skin flaps via autophagy.
Tu Z, Jiang X, Li Y, Yang S, Lin D, Shi Y, Mao C, Zhang X, Lin C
American journal of translational research 2021;13(3):1337-1351
American journal of translational research 2021;13(3):1337-1351
Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.
Zhou F, Zhang X, Jiang L, Li S, Chen Y, Wu J
Frontiers in pharmacology 2021;12:667524
Frontiers in pharmacology 2021;12:667524
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Wang J, Su Q, Wu Q, Chen K, Ullah A, Ghauri MA, Zhang Y
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Archives of pharmacal research 2021 Nov;44(11):1025-1036
1,3-dichloro-2-propanol induced hepatic lipid accumulation by inhibiting autophagy via AKT/mTOR/FOXO1 pathway in mice.
Fan Y, Lu J, Liu J, Zhang R, Yu Z, Guan S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112578
Prenatal-onset of congenital neuronal ceroid lipofuscinosis with a novel CTSD mutation.
Chartier S, Boutaud L, Le Guillou E, Alby C, Billon C, Millischer AE, Caillaud C, Galmiche L, Mechler C, Sonigo P, Boddaert N, Lyonnet S, Rondeau S, Bole-Feysot C, Masson C, Ville Y, Roth P, Desguerre I, Encha-Razavi F, Attie-Bitach T
Birth defects research 2021 Nov;113(18):1324-1332
Birth defects research 2021 Nov;113(18):1324-1332
Exopolysaccharides from Bifidobacterium animalis Ameliorate Escherichia coli-Induced IPEC-J2 Cell Damage via Inhibiting Apoptosis and Restoring Autophagy.
Yuan L, Chu B, Chen S, Li Y, Liu N, Zhu Y, Zhou D
Microorganisms 2021 Nov 16;9(11)
Microorganisms 2021 Nov 16;9(11)
Exenatide improves random-pattern skin flap survival via TFE3 mediated autophagy augment.
Li J, Chen H, Lou J, Bao G, Wu C, Lou Z, Wang X, Ding J, Li Z, Xiao J, Xu H, Gao W, Zhou K
Journal of cellular physiology 2021 May;236(5):3641-3659
Journal of cellular physiology 2021 May;236(5):3641-3659
Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons.
Zhang X, Wei M, Fan J, Yan W, Zha X, Song H, Wan R, Yin Y, Wang W
Autophagy 2021 Jun;17(6):1519-1542
Autophagy 2021 Jun;17(6):1519-1542
Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective.
Hossain MI, Marcus JM, Lee JH, Garcia PL, Singh V, Shacka JJ, Zhang J, Gropen TI, Falany CN, Andrabi SA
Autophagy 2021 Jun;17(6):1330-1348
Autophagy 2021 Jun;17(6):1330-1348
Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson's disease models.
Dong WL, Zhong JH, Chen YQ, Xie JF, Qin YY, Xu JP, Cai NB, Li MF, Liu L, Wang HT
Acta pharmacologica Sinica 2021 Dec;42(12):1991-2003
Acta pharmacologica Sinica 2021 Dec;42(12):1991-2003
Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD.
Wu Y, Shao W, Todd TW, Tong J, Yue M, Koga S, Castanedes-Casey M, Librero AL, Lee CW, Mackenzie IR, Dickson DW, Zhang YJ, Petrucelli L, Prudencio M
Cell reports 2021 Aug 24;36(8):109581
Cell reports 2021 Aug 24;36(8):109581
Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis.
Zummo FP, Krishnanda SI, Georgiou M, O'Harte FP, Parthsarathy V, Cullen KS, Honkanen-Scott M, Shaw JA, Lovat PE, Arden C
Autophagy 2021 Aug 2;:1-17
Autophagy 2021 Aug 2;:1-17
Programmed cell death 4 modulates lysosomal function by inhibiting TFEB translation.
Chen X, Guan Y, Zhang Y, Jia Y, Li W, Guo C, Li Y, Wang X, Shi Y, Wang Q, Zhu F, Li Y, Zhang L
Cell death and differentiation 2021 Apr;28(4):1237-1250
Cell death and differentiation 2021 Apr;28(4):1237-1250
DDRGK1, a crucial player of ufmylation system, is indispensable for autophagic degradation by regulating lysosomal function.
Cao Y, Li R, Shen M, Li C, Zou Y, Jiang Q, Liu S, Lu C, Li H, Liu H, Cai Y
Cell death & disease 2021 Apr 20;12(5):416
Cell death & disease 2021 Apr 20;12(5):416
TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7.
Hu J, Ding X, Tian S, Chu Y, Liu Z, Li Y, Li X, Wang G, Wang L, Wang Z
Cell death & disease 2021 Apr 12;12(4):391
Cell death & disease 2021 Apr 12;12(4):391
Hydroxysafflor yellow A promotes multiterritory perforating flap survival: an experimental study.
Zhang C, Shao Z, Chen Z, Lin C, Hu S, Lou Z, Li J, Zheng X, Lin N, Gao W
American journal of translational research 2020;12(8):4781-4794
American journal of translational research 2020;12(8):4781-4794
Detrimental Effect of Sitagliptin Induced Autophagy on Multiterritory Perforator Flap Survival.
Chen Z, Zhang C, Ma H, Huang Z, Li J, Lou J, Li B, Tu Q, Gao W
Frontiers in pharmacology 2020;11:951
Frontiers in pharmacology 2020;11:951
Staphylococcus aureus Avoids Autophagy Clearance of Bovine Mammary Epithelial Cells by Impairing Lysosomal Function.
Geng N, Wang X, Yu X, Wang R, Zhu Y, Zhang M, Liu J, Liu Y
Frontiers in immunology 2020;11:746
Frontiers in immunology 2020;11:746
Butylphthalide Inhibits Autophagy and Promotes Multiterritory Perforator Flap Survival.
Li B, Chen Z, Luo X, Zhang C, Chen H, Wang S, Zhao M, Ma H, Liu J, Cheng M, Yang Y, Yan H
Frontiers in pharmacology 2020;11:612932
Frontiers in pharmacology 2020;11:612932
Notoginsenoside R1 Protects Against the Acrylamide-Induced Neurotoxicity via Upregulating Trx-1-Mediated ITGAV Expression: Involvement of Autophagy.
Wang W, Huang L, Thomas ER, Hu Y, Zeng F, Li X
Frontiers in pharmacology 2020;11:559046
Frontiers in pharmacology 2020;11:559046
Baicalein Attenuates Pyroptosis and Endoplasmic Reticulum Stress Following Spinal Cord Ischemia-Reperfusion Injury via Autophagy Enhancement.
Wu C, Xu H, Li J, Hu X, Wang X, Huang Y, Li Y, Sheng S, Wang Y, Xu H, Ni W, Zhou K
Frontiers in pharmacology 2020;11:1076
Frontiers in pharmacology 2020;11:1076
TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress.
Zhou K, Zheng Z, Li Y, Han W, Zhang J, Mao Y, Chen H, Zhang W, Liu M, Xie L, Zhang H, Xu H, Xiao J
Theranostics 2020;10(20):9280-9302
Theranostics 2020;10(20):9280-9302
Lysosomal dysfunction and autophagy blockade contribute to autophagy-related cancer suppressing peptide-induced cytotoxic death of cervical cancer cells through the AMPK/mTOR pathway.
Yang Y, Wang Q, Song D, Zen R, Zhang L, Wang Y, Yang H, Zhang D, Jia J, Zhang J, Wang J
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):197
Journal of experimental & clinical cancer research : CR 2020 Sep 22;39(1):197
Autophagic blockage by bismuth sulfide nanoparticles inhibits migration and invasion of HepG2 cells.
Hao BM, Liu YN, Zhang CY, Li GQ, Wang WN, Xu WD, Zha ZB, Wang F, Li C, Miao ZH, Yang XX, Chen YL, Qian HS, Zhou W
Nanotechnology 2020 Nov 13;31(46):465102
Nanotechnology 2020 Nov 13;31(46):465102
Heat shock factor 4 regulates lysosome activity by modulating the αB-crystallin-ATP6V1A-mTOR complex in ocular lens.
Cui X, Feng R, Wang J, Du C, Pi X, Chen D, Li J, Li H, Zhang J, Zhang J, Mu H, Zhang F, Liu M, Hu Y
Biochimica et biophysica acta. General subjects 2020 Mar;1864(3):129496
Biochimica et biophysica acta. General subjects 2020 Mar;1864(3):129496
An Experimental Model of Neurodegenerative Disease Based on Porcine Hemagglutinating Encephalomyelitis Virus-Related Lysosomal Abnormalities.
Lan Y, Li Z, Wang Z, Wang X, Wang G, Zhang J, Hu S, Zhao K, Xu B, Gao F, He W
Molecular neurobiology 2020 Dec;57(12):5299-5306
Molecular neurobiology 2020 Dec;57(12):5299-5306
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Chen M, Ding Y, Ke Y, Zeng Y, Liu N, Zhong Y, Hua X, Li Z, Xiong Y, Wu C, Yu H
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
Artificial cells, nanomedicine, and biotechnology 2020 Dec;48(1):824-833
Combined toxic effects of CBNPs and Pb on rat alveolar macrophage apoptosis and autophagy flux.
Guan S, Tao S, Huang Y, Jin Y, Hu Y, Lu J
Ecotoxicology and environmental safety 2020 Dec 1;205:111062
Ecotoxicology and environmental safety 2020 Dec 1;205:111062
Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting.
Evans AJ, Daly JL, Anuar ANK, Simonetti B, Cullen PJ
Journal of cell science 2020 Aug 3;133(15)
Journal of cell science 2020 Aug 3;133(15)
27-Hydroxycholesterol Contributes to Lysosomal Membrane Permeabilization-Mediated Pyroptosis in Co-cultured SH-SY5Y Cells and C6 Cells.
Chen S, Zhou C, Yu H, Tao L, An Y, Zhang X, Wang Y, Wang Y, Xiao R
Frontiers in molecular neuroscience 2019;12:14
Frontiers in molecular neuroscience 2019;12:14
Protective effects of resveratrol on random-pattern skin flap survival: an experimental study.
Lin J, Lin R, Li S, Wu H, Ding J, Xiang G, Li S, Wang Y, Lin D, Gao W, Kong J, Xu H, Zhou K
American journal of translational research 2019;11(1):379-392
American journal of translational research 2019;11(1):379-392
Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy.
Li J, Bao G, ALyafeai E, Ding J, Li S, Sheng S, Shen Z, Jia Z, Lin C, Zhang C, Lou Z, Xu H, Gao W, Zhou K
Frontiers in pharmacology 2019;10:1017
Frontiers in pharmacology 2019;10:1017
FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival.
Zhou K, Chen H, Lin J, Xu H, Wu H, Bao G, Li J, Deng X, Shui X, Gao W, Ding J, Xiao J, Xu H
Cell death & disease 2019 Nov 18;10(12):872
Cell death & disease 2019 Nov 18;10(12):872
Inhibition of PI3K/mTOR increased the sensitivity of hepatocellular carcinoma cells to cisplatin via interference with mitochondrial-lysosomal crosstalk.
Sheng J, Shen L, Sun L, Zhang X, Cui R, Wang L
Cell proliferation 2019 May;52(3):e12609
Cell proliferation 2019 May;52(3):e12609
ERβ promotes Aβ degradation via the modulation of autophagy.
Wei Y, Zhou J, Wu J, Huang J
Cell death & disease 2019 Jul 22;10(8):565
Cell death & disease 2019 Jul 22;10(8):565
Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy.
Lin J, Lin R, Li S, Wu H, Ding J, Xiang G, Li S, Wang Y, Lin D, Gao W, Kong J, Xu H, Zhou K
Frontiers in pharmacology 2018;9:1178
Frontiers in pharmacology 2018;9:1178
NDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy.
Wang H, Li W, Xu J, Zhang T, Zuo D, Zhou Z, Lin B, Wang G, Wang Z, Sun W, Sun M, Chang S, Cai Z, Hua Y
Cell death & disease 2017 Sep 14;8(9):e3048
Cell death & disease 2017 Sep 14;8(9):e3048
Green Tea Polyphenols, Mimicking the Effects of Dietary Restriction, Ameliorate High-Fat Diet-Induced Kidney Injury via Regulating Autophagy Flux.
Xie X, Yi W, Zhang P, Wu N, Yan Q, Yang H, Tian C, Xiang S, Du M, Getachew Assefa E, Zuo X, Ying C
Nutrients 2017 May 14;9(5)
Nutrients 2017 May 14;9(5)
TMEM175 deficiency impairs lysosomal and mitochondrial function and increases α-synuclein aggregation.
Jinn S, Drolet RE, Cramer PE, Wong AH, Toolan DM, Gretzula CA, Voleti B, Vassileva G, Disa J, Tadin-Strapps M, Stone DJ
Proceedings of the National Academy of Sciences of the United States of America 2017 Feb 28;114(9):2389-2394
Proceedings of the National Academy of Sciences of the United States of America 2017 Feb 28;114(9):2389-2394
Epigallocatechin-3-gallate inhibits H2O2-induced apoptosis in Mouse Vascular Smooth Muscle Cells via 67kD Laminin Receptor.
Yan X, Li Y, Yu H, Wang W, Wu C, Yang Y, Hu Y, Shi X, Li J
Scientific reports 2017 Aug 10;7(1):7774
Scientific reports 2017 Aug 10;7(1):7774
Tetrandrine is a potent cell autophagy agonist via activated intracellular reactive oxygen species.
Wang H, Liu T, Li L, Wang Q, Yu C, Liu X, Li W
Cell & bioscience 2015;5:4
Cell & bioscience 2015;5:4
Synergistic anti-tumour effects of tetrandrine and chloroquine combination therapy in human cancer: a potential antagonistic role for p21.
Mei L, Chen Y, Wang Z, Wang J, Wan J, Yu C, Liu X, Li W
British journal of pharmacology 2015 May;172(9):2232-45
British journal of pharmacology 2015 May;172(9):2232-45
Citreoviridin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis in Human Liver HepG2 Cells.
Wang Y, Liu Y, Liu X, Jiang L, Yang G, Sun X, Geng C, Li Q, Yao X, Chen M
Toxins 2015 Aug 6;7(8):3030-44
Toxins 2015 Aug 6;7(8):3030-44
Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells.
Liu T, Men Q, Wu G, Yu C, Huang Z, Liu X, Li W
Oncotarget 2015 Apr 10;6(10):7992-8006
Oncotarget 2015 Apr 10;6(10):7992-8006
Brucine, an alkaloid from seeds of Strychnos nux-vomica Linn., represses hepatocellular carcinoma cell migration and metastasis: the role of hypoxia inducible factor 1 pathway.
Shu G, Mi X, Cai J, Zhang X, Yin W, Yang X, Li Y, Chen L, Deng X
Toxicology letters 2013 Oct 24;222(2):91-101
Toxicology letters 2013 Oct 24;222(2):91-101
Proteomic features of potential tumor suppressor NESG1 in nasopharyngeal carcinoma.
Liu Z, Chen C, Yang H, Zhang Y, Long J, Long X, Fang W
Proteomics 2012 Nov;12(22):3416-25
Proteomics 2012 Nov;12(22):3416-25
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 21327-1-AP(CTSD antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CTSD antibody 21327-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human hepatocirrhosis using 21327-1-AP(CTSD antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human hepatocirrhosis using 21327-1-AP(CTSD antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue