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- References [4]
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- Product number
- NB600-1295 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB600-1295, RRID:AB_10003401
- Product name
- Mouse Monoclonal Cathepsin D Antibody
- Antibody type
- Monoclonal
- Description
- Unpurified. Recognizes cathepsin D (34 kDa and weaker band at 52 kDa) in immunoblotting. Does not react with bovine cathepsin D and B, or with human cathepsin types B, C, G or H.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references MYC degradation under low O2 tension promotes survival by evading hypoxia-induced cell death.
BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria.
Identification of 14-3-3γ as a Mieap-interacting protein and its role in mitochondrial quality control.
Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria.
Wong WJ, Qiu B, Nakazawa MS, Qing G, Simon MC
Molecular and cellular biology 2013 Sep;33(17):3494-504
Molecular and cellular biology 2013 Sep;33(17):3494-504
BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria.
Nakamura Y, Kitamura N, Shinogi D, Yoshida M, Goda O, Murai R, Kamino H, Arakawa H
PloS one 2012;7(1):e30767
PloS one 2012;7(1):e30767
Identification of 14-3-3γ as a Mieap-interacting protein and its role in mitochondrial quality control.
Miyamoto T, Kitamura N, Ono M, Nakamura Y, Yoshida M, Kamino H, Murai R, Yamada T, Arakawa H
Scientific reports 2012;2:379
Scientific reports 2012;2:379
Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria.
Kitamura N, Nakamura Y, Miyamoto Y, Miyamoto T, Kabu K, Yoshida M, Futamura M, Ichinose S, Arakawa H
PloS one 2011 Jan 17;6(1):e16060
PloS one 2011 Jan 17;6(1):e16060
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Supportive validation
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Cathepsin D Antibody (NB600-1295) - WB analysis of MCF7 Human breast carcinoma cells were separated on SDS-PAGE and probed with Monoclonal AB to Cathepsin D (NB600-1295) at 1/4,000. The antibody was developed with AlkPhos APA mouse Fab ads HIgG conjugate (Cat. No. A1293) and a NBT/BCIP substrate.
