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Immunocytochemistry
Immunoelectron microscopyAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Immunoelectron microscopy [1]
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- Product number
- 621202 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#621202, RRID:AB_2250964
- Product name
- Purified anti-Myosin heavy chain
- Antibody type
- Polyclonal
- Antigen
- Recombinant
- Description
- Myosin heavy chain is an actin-based motor protein with an approximate molecular weight of 223 kD. Myosin heavy chain can be split into 1 light meromysin and 1 heavy meromysin chain (and further into 2 globular subfragments and 1 rod-shaped subfragment). This protein is highly expressed in muscle. Motor proteins that convert chemical energy derived from ATP hydrolysis into mechanical force that drives motile processes such as cytokinesis, vesicular transport, and cellular locomotion. Myosin heavy chain is modified by acetylation in cysteine residues in the S1 domain for myosin ATPase activity. Muscle myosin is a hexameric protein consisting of 2 heavy chain subunits and 2 alkali light chain subunits and 2 regulatory light chain subunits that forms filaments.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 100 µl
- Storage
- Upon receipt, store frozen at -20° C.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Hela cells stained with purified rabbit polyclonal antibody against Myosin heavy chain (poly6212), followed by Cy3 conjugated Donkey anti-rabbit IgG and DAPI.
- Conjugate
- Unconjugated
