Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PAB10066 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB10066, RRID:AB_1713915
- Product name
- SH3BP2 (phospho S427) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of SH3BP2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references A missense mutation in the SH3BP2 gene on chromosome 4p16.3 found in a case of nonfamilial cherubism.
The chaperone protein 14-3-3 interacts with 3BP2/SH3BP2 and regulates its adapter function.
Novel mutation in the gene encoding c-Abl-binding protein SH3BP2 causes cherubism.
Imai Y, Kanno K, Moriya T, Kayano S, Seino H, Matsubara Y, Yamada A
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2003 Nov;40(6):632-8
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2003 Nov;40(6):632-8
The chaperone protein 14-3-3 interacts with 3BP2/SH3BP2 and regulates its adapter function.
Foucault I, Liu YC, Bernard A, Deckert M
The Journal of biological chemistry 2003 Feb 28;278(9):7146-53
The Journal of biological chemistry 2003 Feb 28;278(9):7146-53
Novel mutation in the gene encoding c-Abl-binding protein SH3BP2 causes cherubism.
Lo B, Faiyaz-Ul-Haque M, Kennedy S, Aviv R, Tsui LC, Teebi AS
American journal of medical genetics. Part A 2003 Aug 15;121A(1):37-40
American journal of medical genetics. Part A 2003 Aug 15;121A(1):37-40
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis is shown using SH3BP2 (phospho S427) polyclonal antibody (Cat # PAB10066) to detect endogenous protein present in unstimulated human whole cell lysates.The bandas indicated by the arrowheads is evident in both M059 cells (panel A) and PC-3 cells (panel B).Comparison to a molecular weight marker indicatesa band of ~60 KDa corresponding to human SH3BP2 protein.The blot was incubated with a 1:500 dilutionof the antibody at room temperature followed by detection using standard techniques.Personal communication Steven Pelech, Kinexus Inc.
