Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN954894 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Sp1 Transcription Factor (SP1) (AA 684-715), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Purified through a Protein A column followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 684-715, C-Term
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Transcriptional control of KCNQ channel genes and the regulation of neuronal excitability.
SP1 acts as a key factor, contributes to upregulation of ADAM23 expression under serum deprivation.
Zinc finger-zinc finger interaction between the transcription factors, GATA-1 and Sp1.
Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73gamma in lung cancer.
Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation.
Mucha M, Ooi L, Linley JE, Mordaka P, Dalle C, Robertson B, Gamper N, Wood IC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Oct 6;30(40):13235-45
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Oct 6;30(40):13235-45
SP1 acts as a key factor, contributes to upregulation of ADAM23 expression under serum deprivation.
Pan Q, Yang S, Wei Y, Sun F, Li Z
Biochemical and biophysical research communications 2010 Oct 15;401(2):306-12
Biochemical and biophysical research communications 2010 Oct 15;401(2):306-12
Zinc finger-zinc finger interaction between the transcription factors, GATA-1 and Sp1.
Imanishi M, Imamura C, Higashi C, Yan W, Negi S, Futaki S, Sugiura Y
Biochemical and biophysical research communications 2010 Oct 1;400(4):625-30
Biochemical and biophysical research communications 2010 Oct 1;400(4):625-30
Sp1 binds to the external promoter of the p73 gene and induces the expression of TAp73gamma in lung cancer.
Logotheti S, Michalopoulos I, Sideridou M, Daskalos A, Kossida S, Spandidos DA, Field JK, Vojtesek B, Liloglou T, Gorgoulis V, Zoumpourlis V
The FEBS journal 2010 Jul;277(14):3014-27
The FEBS journal 2010 Jul;277(14):3014-27
Inhibition of NFkappaB and pancreatic cancer cell and tumor growth by curcumin is dependent on specificity protein down-regulation.
Jutooru I, Chadalapaka G, Lei P, Safe S
The Journal of biological chemistry 2010 Aug 13;285(33):25332-44
The Journal of biological chemistry 2010 Aug 13;285(33):25332-44
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Supportive validation
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS