624702

antibody from BioLegend
Targeting: SP1
Provider product page for 624702
Western blot
Immunohistochemistry

Antibody data

Product number
624702 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#624702, RRID:AB_2194178
Product name
Purified anti-Sp1
Antibody type
Polyclonal
Antigen
Peptide mapping to internal domain of human Sp1
Description
The sequence-specific transcription factor Sp1 binds GC box sequences in the promoters of a variety of genes. The 97 kD Sp1 transcription factor contains two zinc finger domains that determine sequence specificity of binding to the 5'-GGGGCGGGGC-3'. This transcription factor regulates nucleoside, nucleotide and nucleic acid metabolism and many other "housekeeping" genes. Sp1 can be modified by phosphorylation by the upstream kinase ERK1 and has been shown to interact with a large number of proteins. The transcriptional activity of Sp1 has been shown to be disrupted in early Huntington's disease. The Poly6247 antibody recognizes human, mouse, and rat Sp1 and has been shown to be useful for Western blotting.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Vial size
500 µl
Storage
The antibody solution should be stored undiluted at 4°C. DO NOT FREEZE.
SP1 protein structure - 624702 shown in red.