Antibody data
- Antibody Data
- Antigen structure
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- Product number
- Ab128849 - Provider product page
- Provider
- Aladdin Scientific Corporation
- Product name
- Recombinant SP1 Antibody
- Antibody type
- Recombinant
- Description
- Rabbit anti Human SP1 Antibody, Recombinant (R01-9G6), could be used for WB, IHC, IF/ICC and so on.Application:WB: 1/500-1/1000IHC: 1/50-1/100IF/ICC:1/50-1/200Protein Function:Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
AA 554-568
- Antibody clone number
- R01-9G6
- Vial size
- 100μl,10μl,1ml,50μl
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
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