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- Antigen structure
- References [16]
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- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [2]
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- Product number
- ABIN151783 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Telomerase Reverse Transcriptase (TERT) antibody
- Antibody type
- Monoclonal
- Description
- Unpurified
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgM
- Antibody clone number
- 2C4
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe.
Telomerase reverse transcriptase acts in a feedback loop with NF-κB pathway to regulate macrophage polarization in alcoholic liver disease.
TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome.
Effects of smoking on human telomerase reverse transcriptase expression in the skin.
Universal cancer peptide-based therapeutic vaccine breaks tolerance against telomerase and eradicates established tumor.
Activating enhancer-binding protein-2β nucleolar localization predicts poor survival after stage I non-small cell lung cancer resection.
Synthetic siRNA targeting the breakpoint of EWS/Fli-1 inhibits growth of Ewing sarcoma xenografts in a mouse model.
Interferon-inducible IFI16, a negative regulator of cell growth, down-regulates expression of human telomerase reverse transcriptase (hTERT) gene.
Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues.
Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues.
Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis.
Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths.
Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cells.
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.
Nucleolin interacts with telomerase.
Telomerase maintains telomere structure in normal human cells.
Margalef P, Kotsantis P, Borel V, Bellelli R, Panier S, Boulton SJ
Cell 2018 Jan 25;172(3):439-453.e14
Cell 2018 Jan 25;172(3):439-453.e14
Telomerase reverse transcriptase acts in a feedback loop with NF-κB pathway to regulate macrophage polarization in alcoholic liver disease.
Wu XQ, Yang Y, Li WX, Cheng YH, Li XF, Huang C, Meng XM, Wu BM, Liu XH, Zhang L, Lv XW, Li J
Scientific reports 2016 Jan 4;6:18685
Scientific reports 2016 Jan 4;6:18685
TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome.
Chen J, Yao ZX, Chen JS, Gi YJ, Muñoz NM, Kundra S, Herlong HF, Jeong YS, Goltsov A, Ohshiro K, Mistry NA, Zhang J, Su X, Choufani S, Mitra A, Li S, Mishra B, White J, Rashid A, Wang AY, Javle M, Davila M, Michaely P, Weksberg R, Hofstetter WL, Finegold MJ, Shay JW, Machida K, Tsukamoto H, Mishra L
The Journal of clinical investigation 2016 Feb;126(2):527-42
The Journal of clinical investigation 2016 Feb;126(2):527-42
Effects of smoking on human telomerase reverse transcriptase expression in the skin.
Lotfi RA, El Zawahry KM, Kamar ZA, Hashem Z
International journal of dermatology 2014 Oct;53(10):1205-12
International journal of dermatology 2014 Oct;53(10):1205-12
Universal cancer peptide-based therapeutic vaccine breaks tolerance against telomerase and eradicates established tumor.
Dosset M, Godet Y, Vauchy C, Beziaud L, Lone YC, Sedlik C, Liard C, Levionnois E, Clerc B, Sandoval F, Daguindau E, Wain-Hobson S, Tartour E, Langlade-Demoyen P, Borg C, Adotévi O
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Nov 15;18(22):6284-95
Clinical cancer research : an official journal of the American Association for Cancer Research 2012 Nov 15;18(22):6284-95
Activating enhancer-binding protein-2β nucleolar localization predicts poor survival after stage I non-small cell lung cancer resection.
Kim MP, Chen Y, Bekele BN, Lopez A, Khanna A, Chen JQ, Spitz MR, Behrens C, Solis L, Wismach M, Ji L, Wistuba II, Roth JA, Katz RL
The Annals of thoracic surgery 2011 Sep;92(3):1044-50
The Annals of thoracic surgery 2011 Sep;92(3):1044-50
Synthetic siRNA targeting the breakpoint of EWS/Fli-1 inhibits growth of Ewing sarcoma xenografts in a mouse model.
Takigami I, Ohno T, Kitade Y, Hara A, Nagano A, Kawai G, Saitou M, Matsuhashi A, Yamada K, Shimizu K
International journal of cancer 2011 Jan 1;128(1):216-26
International journal of cancer 2011 Jan 1;128(1):216-26
Interferon-inducible IFI16, a negative regulator of cell growth, down-regulates expression of human telomerase reverse transcriptase (hTERT) gene.
Song LL, Ponomareva L, Shen H, Duan X, Alimirah F, Choubey D
PloS one 2010 Jan 5;5(1):e8569
PloS one 2010 Jan 5;5(1):e8569
Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues.
Fabricius EM, Kruse-Boitschenko U, Khoury R, Wildner GP, Raguse JD, Klein M
International journal of oncology 2009 May;34(5):1257-79
International journal of oncology 2009 May;34(5):1257-79
Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues.
Fabricius EM, Kruse-Boitschenko U, Khoury R, Wildner GP, Raguse JD, Klein M, Hoffmeister B
International journal of oncology 2009 Dec;35(6):1377-94
International journal of oncology 2009 Dec;35(6):1377-94
Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis.
Zhang Q, Shi S, Liu Y, Uyanne J, Shi Y, Shi S, Le AD
Journal of immunology (Baltimore, Md. : 1950) 2009 Dec 15;183(12):7787-98
Journal of immunology (Baltimore, Md. : 1950) 2009 Dec 15;183(12):7787-98
Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths.
Wu YL, Dudognon C, Nguyen E, Hillion J, Pendino F, Tarkanyi I, Aradi J, Lanotte M, Tong JH, Chen GQ, Ségal-Bendirdjian E
Journal of cell science 2006 Jul 1;119(Pt 13):2797-806
Journal of cell science 2006 Jul 1;119(Pt 13):2797-806
Genistein represses telomerase activity via both transcriptional and posttranslational mechanisms in human prostate cancer cells.
Jagadeesh S, Kyo S, Banerjee PP
Cancer research 2006 Feb 15;66(4):2107-15
Cancer research 2006 Feb 15;66(4):2107-15
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.
Masutomi K, Possemato R, Wong JM, Currier JL, Tothova Z, Manola JB, Ganesan S, Lansdorp PM, Collins K, Hahn WC
Proceedings of the National Academy of Sciences of the United States of America 2005 Jun 7;102(23):8222-7
Proceedings of the National Academy of Sciences of the United States of America 2005 Jun 7;102(23):8222-7
Nucleolin interacts with telomerase.
Khurts S, Masutomi K, Delgermaa L, Arai K, Oishi N, Mizuno H, Hayashi N, Hahn WC, Murakami S
The Journal of biological chemistry 2004 Dec 3;279(49):51508-15
The Journal of biological chemistry 2004 Dec 3;279(49):51508-15
Telomerase maintains telomere structure in normal human cells.
Masutomi K, Yu EY, Khurts S, Ben-Porath I, Currier JL, Metz GB, Brooks MW, Kaneko S, Murakami S, DeCaprio JA, Weinberg RA, Stewart SA, Hahn WC
Cell 2003 Jul 25;114(2):241-53
Cell 2003 Jul 25;114(2):241-53
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