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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- NB100-297 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-297, RRID:AB_10003015
- Product name
- Mouse Monoclonal TERT Antibody
- Antibody type
- Monoclonal
- Description
- Unpurified.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgM
- Vial size
- 0.1 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Telomerase activation as a repair response to radiation-induced DNA damage in Y79 retinoblastoma cells.
EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis.
Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues.
Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues.
Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues.
Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detection.
Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics.
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.
Generation and characterization of iBREC: novel hTERT-immortalized bovine retinal endothelial cells.
Evolving views of telomerase and cancer.
Evolving views of telomerase and cancer.
Akiyama M, Ozaki K, Kawano T, Yamada O, Kawauchi K, Ida H, Yamada H
Cancer letters 2013 Oct 28;340(1):82-7
Cancer letters 2013 Oct 28;340(1):82-7
EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis.
Heeg S, Hirt N, Queisser A, Schmieg H, Thaler M, Kunert H, Quante M, Goessel G, von Werder A, Harder J, Beijersbergen R, Blum HE, Nakagawa H, Opitz OG
Cancer science 2011 Feb;102(2):351-60
Cancer science 2011 Feb;102(2):351-60
Immunohistochemical determination of the appropriate anti-hTERT antibodies for in situ detection of telomerase activity in frozen sections of head and neck squamous cell carcinomas and tumor margin tissues.
Fabricius EM, Kruse-Boitschenko U, Khoury R, Wildner GP, Raguse JD, Klein M
International journal of oncology 2009 May;34(5):1257-79
International journal of oncology 2009 May;34(5):1257-79
Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues.
Fabricius EM, Kruse-Boitschenko U, Khoury R, Wildner GP, Raguse JD, Klein M, Hoffmeister B
International journal of oncology 2009 Dec;35(6):1377-94
International journal of oncology 2009 Dec;35(6):1377-94
Localization of telomerase hTERT protein in frozen sections of basal cell carcinomas (BCC) and tumor margin tissues.
Fabricius EM, Kruse-Boitschenko U, Khoury R, Wildner GP, Raguse JD, Klein M, Hoffmeister B
International journal of oncology 2009 Dec;35(6):1377-94
International journal of oncology 2009 Dec;35(6):1377-94
Quantitation of HER2 and telomerase biomarkers in solid tumors with IgY antibodies and nanocrystal detection.
Xiao Y, Gao X, Gannot G, Emmert-Buck MR, Srivastava S, Wagner PD, Amos MD, Barker PE
International journal of cancer 2008 May 15;122(10):2178-86
International journal of cancer 2008 May 15;122(10):2178-86
Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics.
Zhang JG, Eguchi J, Kruse CA, Gomez GG, Fakhrai H, Schroter S, Ma W, Hoa N, Minev B, Delgado C, Wepsic HT, Okada H, Jadus MR
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Jan 15;13(2 Pt 1):566-575
Clinical cancer research : an official journal of the American Association for Cancer Research 2007 Jan 15;13(2 Pt 1):566-575
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.
Masutomi K, Possemato R, Wong JM, Currier JL, Tothova Z, Manola JB, Ganesan S, Lansdorp PM, Collins K, Hahn WC
Proceedings of the National Academy of Sciences of the United States of America 2005 Jun 7;102(23):8222-7
Proceedings of the National Academy of Sciences of the United States of America 2005 Jun 7;102(23):8222-7
Generation and characterization of iBREC: novel hTERT-immortalized bovine retinal endothelial cells.
Deissler H, Deissler H, Lang GK, Lang GE
International journal of molecular medicine 2005 Jul;16(1):65-70
International journal of molecular medicine 2005 Jul;16(1):65-70
Evolving views of telomerase and cancer.
Blasco MA, Hahn WC
Trends in cell biology 2003 Jun;13(6):289-94
Trends in cell biology 2003 Jun;13(6):289-94
Evolving views of telomerase and cancer.
Blasco MA, Hahn WC
Trends in cell biology 2003 Jun;13(6):289-94
Trends in cell biology 2003 Jun;13(6):289-94
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: TERT Antibody (2D8) [NB100-297] - Analysis of human TERT, using NB100-297. Sample: MJ90 whole cell lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: TERT Antibody (2D8) [NB100-297] - TERT was detected in immersion fixed paraffin-embedded sections of human liver cancer using anti-human mouse monoclonal antibody (Catalog # NB100-297) at 1:600 dilution overnight at 4C. Tissue was stained using the VisuCyte anti-mouse HRP polymer detection reagent (Catalog # VC001) with DAB chromogen (brown) and counterstained with hematoxylin (blue). Images may not be copied, printed or otherwise disseminated without express written permission of Novus Biologicals a bio-techne brand.
