Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
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- Product number
- GTX30410 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX30410, RRID:AB_370403
- Product name
- TERT antibody [2C4]
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse
- Host
- Mouse
Submitted references Telomerase reverse transcriptase suppression inhibits cell proliferation and promotes cell apoptosis in hepatocellular cancer.
The methylation status and expression of human telomerase reverse transcriptase is significantly high in oral carcinogenesis.
Immunohistochemical expression of telomerase in patients with non-small cell lung cancer: prediction of metastasis and prognostic significance.
Interleukin-1β promotes ovarian tumorigenesis through a p53/NF-κB-mediated inflammatory response in stromal fibroblasts.
Telomerase as an important target of androgen signaling blockade for prostate cancer treatment.
Shen Y, Xi F, Li H, Luo Y, Chen C, Wang L
IUBMB life 2018 Jul;70(7):642-648
IUBMB life 2018 Jul;70(7):642-648
The methylation status and expression of human telomerase reverse transcriptase is significantly high in oral carcinogenesis.
Haraguchi K, Yada N, Sato S, Habu M, Hayakawa M, Takahashi O, Sasaguri M, Takenaka S, Yoshioka I, Matsuo K, Tominaga K
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2017 Sep;125(9):797-807
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2017 Sep;125(9):797-807
Immunohistochemical expression of telomerase in patients with non-small cell lung cancer: prediction of metastasis and prognostic significance.
Aras G, Kanmaz D, Urer N, Purisa S, Kadakal F, Yentürk E, Tuncay E
Anticancer research 2013 Jun;33(6):2643-50
Anticancer research 2013 Jun;33(6):2643-50
Interleukin-1β promotes ovarian tumorigenesis through a p53/NF-κB-mediated inflammatory response in stromal fibroblasts.
Schauer IG, Zhang J, Xing Z, Guo X, Mercado-Uribe I, Sood AK, Huang P, Liu J
Neoplasia (New York, N.Y.) 2013 Apr;15(4):409-20
Neoplasia (New York, N.Y.) 2013 Apr;15(4):409-20
Telomerase as an important target of androgen signaling blockade for prostate cancer treatment.
Liu S, Qi Y, Ge Y, Duplessis T, Rowan BG, Ip C, Cheng H, Rennie PS, Horikawa I, Lustig AJ, Yu Q, Zhang H, Dong Y
Molecular cancer therapeutics 2010 Jul;9(7):2016-25
Molecular cancer therapeutics 2010 Jul;9(7):2016-25
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Western blot using GTX30410 - TERT at a dilution of 1:500 on MJ90 cells.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Western Blot: Telomerase reverse transcriptase Antibody (2C4) [GTX30410] - 1:500 dilution on MJ90 cells.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Staining of pancreas, acinar epithelial cells and Islet of Langerhans using GTX30410.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Staining of carcinoma showing strong taining of tumor cells.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Flow Cytometry: Telomerase reverse transcriptase Antibody (2C4) [GTX30410] - Staining of NTERA-2 cells using GTX30410 at a 1:200 dilution detected using Dylight-488 conjμgated goat anti-mouse IgM secondary antibody.