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Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Chromatin Immunoprecipitation [1]
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- Product number
- HPA001119 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA001119, RRID:AB_1858930
- Product name
- Anti-YY1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human YY1, Gene description: YY1 transcription factor, Alternative Gene Names: DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1, Validated applications: ChIP, IHC, WB, Uniprot ID: P25490, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Cistrome analysis of YY1 uncovers a regulatory axis of YY1:BRD2/4-PFKP during tumorigenesis of advanced prostate cancer.
Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer.
Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication.
Nectin like-5 overexpression correlates with the malignant phenotype in cutaneous melanoma
Xu C, Tsai YH, Galbo PM, Gong W, Storey AJ, Xu Y, Byrum SD, Xu L, Whang YE, Parker JS, Mackintosh SG, Edmondson RD, Tackett AJ, Huang J, Zheng D, Earp HS, Wang GG, Cai L
Nucleic acids research 2021 May 21;49(9):4971-4988
Nucleic acids research 2021 May 21;49(9):4971-4988
Enhancer mapping uncovers phenotypic heterogeneity and evolution in patients with luminal breast cancer.
Patten DK, Corleone G, Győrffy B, Perone Y, Slaven N, Barozzi I, Erdős E, Saiakhova A, Goddard K, Vingiani A, Shousha S, Pongor LS, Hadjiminas DJ, Schiavon G, Barry P, Palmieri C, Coombes RC, Scacheri P, Pruneri G, Magnani L
Nature medicine 2018 Sep;24(9):1469-1480
Nature medicine 2018 Sep;24(9):1469-1480
Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication.
Kaufhold S, Garbán H, Bonavida B
Journal of experimental & clinical cancer research : CR 2016 May 25;35:84
Journal of experimental & clinical cancer research : CR 2016 May 25;35:84
Nectin like-5 overexpression correlates with the malignant phenotype in cutaneous melanoma
Bevelacqua V, Bevelacqua Y, Candido S, Skarmoutsou E, Amoroso A, Guarneri C, Strazzanti A, Gangemi P, Mazzarino M, D’Amico F, McCubrey J, Libra M, Malaponte G
Oncotarget 2012;3(8):882-892
Oncotarget 2012;3(8):882-892
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- ChIP-Exo-Seq composite graph for Anti-YY1 (HPA001119, Lot B115417) tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh´s Lab at Cornell University.
