BS7717

antibody from Bioworld Technology, Inc

Targeting: MSX2 CRS2, FPP, HOX8, MSH, PFM, PFM1

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS7717

Provider

Bioworld Technology, Inc

Product name

MSX2 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human MSX2.

Description

Msx homeobox genes encode for transcription factors that control morphogenesis and are expressed at sites of epithelial-mesenchymal interaction during embryogenesis, such as the tooth. Two of these genes, Msx-1 and Msx-2, are key factors for the development of tooth and craniofacial skeleton. Msx-1 also down-regulates a master gene of skeletal cells differentiation. Msx-1 and Msx-2 contribute to the initial patterning of dentition as well as playing a pivotal role in terminal cell differentiation. In addition, Msx-1 and Msx-2 are expressed in the epidermis, hair follicles and fibroblasts of the developing fetal skin. In adult skin, Msx-1 and Msx-2 expression is confined to epithelially derived structures. Msx-2 is detected as a diffuse cytoplasmic signal in fetal epidermis and portions of the hair follicle and dermis, but is localized to the nucleus in the adult epidermis. Msx-1 and Msx-2 are also expressed during critical developmental stages of neural tube and neural crest, suggesting that these genes play an important role in organogenesis.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.