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Protein structure
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2BAF190, BRM, hBRM, hSNF2a, SNF2, SNF2L2, SNF2LA, Sth1p, SWI2
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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| NSJ Bioreagents |  RQ7714 |
Polyclonal |
WB
EL
ICC
IHC
FC
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| Proteintech Group | 26613-1-AP |
4 references | Polyclonal |
WB
EL
ICC
IHC
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| LSBio | LS-C30062 |
Polyclonal |
WB
IHC
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| Cell Signaling Technology, Inc | 11966 |
Monoclonal |
WB
ICC
IP
IHC
ChIP
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| Biorbyt | orb1474836 |
Polyclonal |
WB
EL
ICC
IHC
FC
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