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LearnNBP1-90015
antibody from Novus Biologicals
Targeting: SMARCA2
BAF190, BRM, hBRM, hSNF2a, SNF2, SNF2L2, SNF2LA, Sth1p, SWI2
Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Immunohistochemistry [4]
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- Product number
- NBP1-90015 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-90015, RRID:AB_11031434
- Product name
- Rabbit Polyclonal BRM Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human BRM antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.
Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome.
Jelinic P, Schlappe BA, Conlon N, Tseng J, Olvera N, Dao F, Mueller JJ, Hussein Y, Soslow RA, Levine DA
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 Jan;29(1):60-6
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2016 Jan;29(1):60-6
Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome.
Van Houdt JK, Nowakowska BA, Sousa SB, van Schaik BD, Seuntjens E, Avonce N, Sifrim A, Abdul-Rahman OA, van den Boogaard MJ, Bottani A, Castori M, Cormier-Daire V, Deardorff MA, Filges I, Fryer A, Fryns JP, Gana S, Garavelli L, Gillessen-Kaesbach G, Hall BD, Horn D, Huylebroeck D, Klapecki J, Krajewska-Walasek M, Kuechler A, Lines MA, Maas S, Macdermot KD, McKee S, Magee A, de Man SA, Moreau Y, Morice-Picard F, Obersztyn E, Pilch J, Rosser E, Shannon N, Stolte-Dijkstra I, Van Dijck P, Vilain C, Vogels A, Wakeling E, Wieczorek D, Wilson L, Zuffardi O, van Kampen AH, Devriendt K, Hennekam R, Vermeesch JR
Nature genetics 2012 Feb 26;44(4):445-9, S1
Nature genetics 2012 Feb 26;44(4):445-9, S1
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: BRM Antibody [NBP1-90015] - Staining of human cerebral cortex shows moderate to strong nuclear positivity in neuronal cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: BRM Antibody [NBP1-90015] - Staining of human fallopian tube shows strong nuclear positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: BRM Antibody [NBP1-90015] - Staining of human pancreas shows weak to moderate nuclear positivity in exocrine glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: BRM Antibody [NBP1-90015] - Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.
