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LearnPAB1855
antibody from Abnova Corporation
Targeting: PIAS2
ARIP3, miz, PIASX-ALPHA, PIASX-BETA, ZMIZ4
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- PAB1855 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB1855, RRID:AB_1578731
- Product name
- PIAS2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of PIAS2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells.
PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4.
Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter.
Sakurai T, Itoh K, Higashitsuji H, Nagao T, Nonoguchi K, Chiba T, Fujita J
The Journal of biological chemistry 2004 Apr 9;279(15):15505-14
The Journal of biological chemistry 2004 Apr 9;279(15):15505-14
PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4.
Arora T, Liu B, He H, Kim J, Murphy TL, Murphy KM, Modlin RL, Shuai K
The Journal of biological chemistry 2003 Jun 13;278(24):21327-30
The Journal of biological chemistry 2003 Jun 13;278(24):21327-30
Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter.
Wu S, Cetinkaya C, Munoz-Alonso MJ, von der Lehr N, Bahram F, Beuger V, Eilers M, Leon J, Larsson LG
Oncogene 2003 Jan 23;22(3):351-60
Oncogene 2003 Jan 23;22(3):351-60
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with PIAS2 polyclonal antibody (Cat # PAB1855), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
