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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- PAB10001 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB10001, RRID:AB_1674779
- Product name
- DRAM polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to N-terminus of human DRAM.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100 μg
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references DRAM links autophagy to p53 and programmed cell death.
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.
Autophagy as a cell death and tumor suppressor mechanism.
Crighton D, Wilkinson S, Ryan KM
Autophagy 2007 Jan-Feb;3(1):72-4
Autophagy 2007 Jan-Feb;3(1):72-4
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.
Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, Gasco M, Garrone O, Crook T, Ryan KM
Cell 2006 Jul 14;126(1):121-34
Cell 2006 Jul 14;126(1):121-34
Autophagy as a cell death and tumor suppressor mechanism.
Gozuacik D, Kimchi A
Oncogene 2004 Apr 12;23(16):2891-906
Oncogene 2004 Apr 12;23(16):2891-906
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot using DRAM polyclonal antibody (Cat # PAB10001) shows detection of a predominant band at ~33 kDa corresponding to DRAM (arrowhead) in K-562 whole cell lysate.The predicted MW of DRAM is 26 kDa.DRAM was detected using 0.5 ug/mL (lane A), 1.0 ug/mL (lane B) and 2 ug/mL (lane C) concentrations of primary antibody.
