Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PAB13245 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB13245, RRID:AB_10552124
- Product name
- DRAM polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of DRAM.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references TW01001, a novel piperazinedione compound, induces mitotic arrest and autophagy in non-small cell lung cancer A549 cells.
DRAM links autophagy to p53 and programmed cell death.
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.
Autophagy as a cell death and tumor suppressor mechanism.
Chen MC, Chen CH, Liu YN, Wang HP, Pan SL, Teng CM
Cancer letters 2013 Aug 19;336(2):370-8
Cancer letters 2013 Aug 19;336(2):370-8
DRAM links autophagy to p53 and programmed cell death.
Crighton D, Wilkinson S, Ryan KM
Autophagy 2007 Jan-Feb;3(1):72-4
Autophagy 2007 Jan-Feb;3(1):72-4
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.
Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, Gasco M, Garrone O, Crook T, Ryan KM
Cell 2006 Jul 14;126(1):121-34
Cell 2006 Jul 14;126(1):121-34
Autophagy as a cell death and tumor suppressor mechanism.
Gozuacik D, Kimchi A
Oncogene 2004 Apr 12;23(16):2891-906
Oncogene 2004 Apr 12;23(16):2891-906
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of DRAM in 293 cell lysate with DRAM polyclonal antibody (Cat # PAB13245) at (A) 0.5 and (B) 1 ug/mL .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemistry of DRAM in human liver tissue with DRAM polyclonal antibody (Cat # PAB13245) at 2.5 ug/mL .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)