11-1001-25

antibody from ABEOMICS Inc.

Targeting: DRAM1 DRAM, FLJ11259

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

11-1001-25

Provider

ABEOMICS Inc.

Product name

Anti-DRAM Antibody

Antibody type

Polyclonal

Description

DRAM (DNA-damage regulated autophagy modulator 1) with a molecular weight of 26 kDa is a lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. It belongs to DRAM/TMEM150 family. This gene is regulated as part of the p53 tumor suppressor pathway. DRAM has a pseudogene on chromosome 4. It is expressed in embryonic tissues and stem cells. DRAM1 is often found to be under-expressed in many tumor types. It has 2 isoforms produced by alternative splicing.

Reactivity

Human

Host

Rabbit

Antigen sequence

A partial length recombinant DRAM p
rotein (amino acids 1-230) was used
as the immunogen for this antibody
.


Vial size

25 µg

Concentration

0.5 mg/ml

Storage

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing

Western blot

Supportive validation

Submitted by

ABEOMICS Inc. (provider)

Main image

Experimental details

Western blot analysis of DRAM. Anti- DRAM antibody (11-1001) was used at 4 µg/ml on (1) Kidney and (2) Lungs lysates.