BS1769

antibody from Bioworld Technology, Inc
Targeting: SMAD2 JV18-1, MADH2, MADR2
Provider product page for BS1769
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS1769 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS1769, RRID:AB_1914375
Product name
Smad2 (Y216) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 185-234 of Human Smad2.
Description
Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of GFÉÇ/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFÉÇ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFÉÇ signaling by interfering with TGFÉÇ-mediated phosphorylation of other Smad proteins.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SMAD2 protein structure - BS1769 shown in red.