Antibody data

Product number
11-10026 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-Brachyury Antibody
Antibody type
Polyclonal
Description
Brachyury is a transcription factor encoded by T, a member of the T-box gene family, and required for posterior mesoderm formation and differentiation as well as for notochord development. It is expressed in all nascent mesoderm, in the embryo. Along with embryonic differentiation, it is downregulated, restricted into the notochord and the tail bud, and then lost, when notochordal cells are replaced by bone in the vertebral bodies and by the nucleus pulposus in the intervertebral discs. In the adult, brachyury expression has been found in chordoma, a malignant tumor which recapitulates notochord and derives from small collections of notochordal cells which may persist into the adult life.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant Brachy
ury protein (amino acids 200-410) w
as used as the immunogen for this a
ntibody.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
TBXT protein structure - 11-10026 shown in red.