sc-643

antibody from Santa Cruz Biotechnology

Targeting: SP2 KIAA0048

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

sc-643

Provider

Santa Cruz Biotechnology

Proper citation

Santa Cruz Biotechnology Cat#sc-643, RRID:AB_2121523

Product name

Anti-SP2

Antibody type

Polyclonal (Antigen purified)

Antigen

Synthetic peptide

Reactivity

Human

Host

Rabbit

References

Submitted references

Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin.

Yamamoto T, Watanabe K, Inoue N, Nakagawa Y, Ishigaki N, Matsuzaka T, Takeuchi Y, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Yahagi N, Gotoda T, Yamada N, Shimano H
Journal of lipid research 2010 Jul;51(7):1859-70

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Sp2 localizes to subnuclear foci associated with the nuclear matrix.

Moorefield KS, Yin H, Nichols TD, Cathcart C, Simmons SO, Horowitz JM
Molecular biology of the cell 2006 Apr;17(4):1711-22

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E2F suppression and Sp1 overexpression are sufficient to induce the differentiation-specific marker, transglutaminase type 1, in a squamous cell carcinoma cell line

Chung Fai Wong, Liam M Barnes, Alison L Dahler, Louise Smith, Claudia Popa, Magdalena M Serewko-Auret, Nicholas A Saunders
Oncogene 2005 Feb;24(21):3525-3534

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ZBP-89 represses vimentin gene transcription by interacting with the transcriptional activator, Sp1.

Zhang X, Diab IH, Zehner ZE
Nucleic acids research 2003 Jun 1;31(11):2900-14

Immunohistochemistry

Supportive validation

Submitted by

per

Main image

Experimental details

Immunohistochemical staining of human colon shows strong nuclear positivity in glandular cells.

Validation comment

Staining pattern consistent with experimental and/or bioinformatic data.