CABT-B8889

antibody from Creative Diagnostics

Targeting: PACS2 KIAA0602, PACS1L

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

CABT-B8889

Provider

Creative Diagnostics

Product name

Anti-PACS2 polyclonal antibody

Antibody type

Polyclonal

Description

PACS2 (phosphofurin acidic cluster sorting protein 2) is a protein-coding gene. Diseases associated with PACS2 include kaposi's sarcoma, and sarcoma. An important paralog of this gene is PACS1. Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In additon, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Storage

Store at -20°C. Aliquoting is unnecessary for -20°C storage.