Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 349802 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#349802, RRID:AB_10644164
- Product name
- Purified anti-human CD179b (Ig 5)
- Antibody type
- Monoclonal
- Antigen
- CD179b
- Description
- CD179b, also known as Ig Lambda 5, λ5, and Ig omega, is a 22 kD, C-like protein member within the Ig superfamily. λ5 associates with CD179a (VpreB) to form a surrogate light (SL) chain that in turn associates with the IgM heavy chain and the CD79a/CD79b heterodimer to form the pre-B cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation, though it has been reported that the deficiency of CD179a and/or CD179b impairs the maturation of the B cell precursors beyond the pre-B cell stage.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human cell lines REH (pro-B, blue), NALM-6 (pre-B, orange) and Ramos (B cell, open) stained with purified HSL11 conjugated with PE
- Conjugate
- Unconjugated