Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Other assay [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- V3397 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- P-Cadherin Antibody / CDH3
- Antibody type
- Monoclonal
- Description
- Purified
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 6A9
- Vial size
- 20 µg, 100 µg (with BSA, sodium azide), 100 µg (without BSA, sodium azide), 7 ml (prediluted for IHC)
- Concentration
- 0.2 mg/ml
- Storage
- Store the P-Cadherin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Connexins, E-cadherin, Claudin-7 and β-catenin transiently form junctional nexuses during the post-natal mammary gland development.
The cytoplasmic domain of N-cadherin modulates MMP‑9 induction in oral squamous carcinoma cells.
Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis.
Slug (SNAI2) expression in oral SCC cells results in altered cell-cell adhesion and increased motility.
Identification of human embryonic stem cell surface markers by combined membrane-polysome translation state array analysis and immunotranscriptional profiling.
A novel breast cancer cell line initially established from pleural effusion: evolution towards a more aggressive phenotype.
Expression of E-cadherin, P-cadherin and N-cadherin in oral squamous cell carcinoma: correlation with the clinicopathologic features and patient outcome.
Expression of inappropriate cadherins by epithelial tumor cells promotes endocytosis and degradation of E-cadherin via competition for p120(ctn).
R-cadherin influences cell motility via Rho family GTPases.
Differential displacement of classical cadherins by VE-cadherin.
Upregulation of P-cadherin expression in the lesional skin of pemphigus, Hailey-Hailey disease and Darier's disease.
The amino- and carboxyl-terminal tails of (beta)-catenin reduce its affinity for desmoglein 2.
Lack of correlation between serum levels of E- and P-cadherin fragments and the presence of breast cancer.
P-cadherin expression in breast carcinoma indicates poor survival.
Mechanism of extracellular domain-deleted dominant negative cadherins.
Cadherin and catenin expression in normal human bronchial epithelium and non-small cell lung cancer.
Inhibition of cadherin function differentially affects markers of terminal differentiation in cultured human keratinocytes.
E-cadherin and P-cadherin have partially redundant roles in human epidermal stratification.
Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?
Expression of P-cadherin identifies prostate-specific-antigen-negative cells in epithelial tissues of male sexual accessory organs and in prostatic carcinomas. Implications for prostate cancer biology.
Plakoglobin domains that define its association with the desmosomal cadherins and the classical cadherins: identification of unique and shared domains.
Dianati E, Poiraud J, Weber-Ouellette A, Plante I
Developmental biology 2016 Aug 1;416(1):52-68
Developmental biology 2016 Aug 1;416(1):52-68
The cytoplasmic domain of N-cadherin modulates MMP‑9 induction in oral squamous carcinoma cells.
Walker A, Frei R, Lawson KR
International journal of oncology 2014 Oct;45(4):1699-706
International journal of oncology 2014 Oct;45(4):1699-706
Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis.
Gautrot JE, Wang C, Liu X, Goldie SJ, Trappmann B, Huck WT, Watt FM
Biomaterials 2012 Jul;33(21):5221-9
Biomaterials 2012 Jul;33(21):5221-9
Slug (SNAI2) expression in oral SCC cells results in altered cell-cell adhesion and increased motility.
Katafiasz D, Smith LM, Wahl JK 3rd
Cell adhesion & migration 2011 Jul-Aug;5(4):315-22
Cell adhesion & migration 2011 Jul-Aug;5(4):315-22
Identification of human embryonic stem cell surface markers by combined membrane-polysome translation state array analysis and immunotranscriptional profiling.
Kolle G, Ho M, Zhou Q, Chy HS, Krishnan K, Cloonan N, Bertoncello I, Laslett AL, Grimmond SM
Stem cells (Dayton, Ohio) 2009 Oct;27(10):2446-56
Stem cells (Dayton, Ohio) 2009 Oct;27(10):2446-56
A novel breast cancer cell line initially established from pleural effusion: evolution towards a more aggressive phenotype.
Schmidt M, Khan A, Schmidt AM, Heinze B, Hack E, Waltenberger J, Kreienberg R
International journal of oncology 2007 Mar;30(3):565-72
International journal of oncology 2007 Mar;30(3):565-72
Expression of E-cadherin, P-cadherin and N-cadherin in oral squamous cell carcinoma: correlation with the clinicopathologic features and patient outcome.
Pyo SW, Hashimoto M, Kim YS, Kim CH, Lee SH, Johnson KR, Wheelock MJ, Park JU
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 2007 Jan;35(1):1-9
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 2007 Jan;35(1):1-9
Expression of inappropriate cadherins by epithelial tumor cells promotes endocytosis and degradation of E-cadherin via competition for p120(ctn).
Maeda M, Johnson E, Mandal SH, Lawson KR, Keim SA, Svoboda RA, Caplan S, Wahl JK 3rd, Wheelock MJ, Johnson KR
Oncogene 2006 Aug 3;25(33):4595-604
Oncogene 2006 Aug 3;25(33):4595-604
R-cadherin influences cell motility via Rho family GTPases.
Johnson E, Theisen CS, Johnson KR, Wheelock MJ
The Journal of biological chemistry 2004 Jul 23;279(30):31041-9
The Journal of biological chemistry 2004 Jul 23;279(30):31041-9
Differential displacement of classical cadherins by VE-cadherin.
Jaggi M, Wheelock MJ, Johnson KR
Cell communication & adhesion 2002 Mar-Apr;9(2):103-15
Cell communication & adhesion 2002 Mar-Apr;9(2):103-15
Upregulation of P-cadherin expression in the lesional skin of pemphigus, Hailey-Hailey disease and Darier's disease.
Hakuno M, Akiyama M, Shimizu H, Wheelock MJ, Nishikawa T
Journal of cutaneous pathology 2001 Jul;28(6):277-81
Journal of cutaneous pathology 2001 Jul;28(6):277-81
The amino- and carboxyl-terminal tails of (beta)-catenin reduce its affinity for desmoglein 2.
Wahl JK3rd, Nieset JE, Sacco-Bubulya PA, Sadler TM, Johnson KR, Wheelock MJ
Journal of cell science 2000 May;113 ( Pt 10):1737-45
Journal of cell science 2000 May;113 ( Pt 10):1737-45
Lack of correlation between serum levels of E- and P-cadherin fragments and the presence of breast cancer.
Knudsen KA, Lin CY, Johnson KR, Wheelock MJ, Keshgegian AA, Soler AP
Human pathology 2000 Aug;31(8):961-5
Human pathology 2000 Aug;31(8):961-5
P-cadherin expression in breast carcinoma indicates poor survival.
Peralta Soler A, Knudsen KA, Salazar H, Han AC, Keshgegian AA
Cancer 1999 Oct 1;86(7):1263-72
Cancer 1999 Oct 1;86(7):1263-72
Mechanism of extracellular domain-deleted dominant negative cadherins.
Nieman MT, Kim JB, Johnson KR, Wheelock MJ
Journal of cell science 1999 May;112 ( Pt 10):1621-32
Journal of cell science 1999 May;112 ( Pt 10):1621-32
Cadherin and catenin expression in normal human bronchial epithelium and non-small cell lung cancer.
Smythe WR, Williams JP, Wheelock MJ, Johnson KR, Kaiser LR, Albelda SM
Lung cancer (Amsterdam, Netherlands) 1999 Jun;24(3):157-68
Lung cancer (Amsterdam, Netherlands) 1999 Jun;24(3):157-68
Inhibition of cadherin function differentially affects markers of terminal differentiation in cultured human keratinocytes.
Hines MD, Jin HC, Wheelock MJ, Jensen PJ
Journal of cell science 1999 Dec;112 ( Pt 24):4569-79
Journal of cell science 1999 Dec;112 ( Pt 24):4569-79
E-cadherin and P-cadherin have partially redundant roles in human epidermal stratification.
Jensen PJ, Telegan B, Lavker RM, Wheelock MJ
Cell and tissue research 1997 May;288(2):307-16
Cell and tissue research 1997 May;288(2):307-16
Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?
Zhou Y, Fisher SJ, Janatpour M, Genbacev O, Dejana E, Wheelock M, Damsky CH
The Journal of clinical investigation 1997 May 1;99(9):2139-51
The Journal of clinical investigation 1997 May 1;99(9):2139-51
Expression of P-cadherin identifies prostate-specific-antigen-negative cells in epithelial tissues of male sexual accessory organs and in prostatic carcinomas. Implications for prostate cancer biology.
Soler AP, Harner GD, Knudsen KA, McBrearty FX, Grujic E, Salazar H, Han AC, Keshgegian AA
The American journal of pathology 1997 Aug;151(2):471-8
The American journal of pathology 1997 Aug;151(2):471-8
Plakoglobin domains that define its association with the desmosomal cadherins and the classical cadherins: identification of unique and shared domains.
Wahl JK, Sacco PA, McGranahan-Sadler TM, Sauppé LM, Wheelock MJ, Johnson KR
Journal of cell science 1996 May;109 ( Pt 5):1143-54
Journal of cell science 1996 May;109 ( Pt 5):1143-54
No comments: Submit comment
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- Western blot testing of human A431 cell lysate with P-Cadherin antibody (clone 6A9). Expected molecular weight: ~91 (unmodified), 100~130 kDa (glycosylated).
Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- SDS-PAGE Analysis of Purified, BSA-Free P-Cadherin Antibody (clone 6A9). Confirmation of Integrity and Purity of the Antibody.