NBP1-89839

antibody from Novus Biologicals

Targeting: RSPH1 CILD24, FLJ32753, RSP44, RSPH10A, TSGA2

Western blot (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

NBP1-89839

Provider

Novus Biologicals

Proper citation

Novus Cat#NBP1-89839, RRID:AB_11013452

Product name

Rabbit Polyclonal TSGA2 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Specificity of human TSGA2 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

Reactivity

Human, Mouse

Host

Rabbit

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

References

Submitted references

Mice with a Deletion of Rsph1 Exhibit a Low Level of Mucociliary Clearance and Develop a Primary Ciliary Dyskinesia Phenotype.

Yin W, Livraghi-Butrico A, Sears PR, Rogers TD, Burns KA, Grubb BR, Ostrowski LE
American journal of respiratory cell and molecular biology 2019 Sep;61(3):312-321

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Targeted NGS gene panel identifies mutations in RSPH1 causing primary ciliary dyskinesia and a common mechanism for ciliary central pair agenesis due to radial spoke defects.

Onoufriadis A, Shoemark A, Schmidts M, Patel M, Jimenez G, Liu H, Thomas B, Dixon M, Hirst RA, Rutman A, Burgoyne T, Williams C, Scully J, Bolard F, Lafitte JJ, Beales PL, Hogg C, Yang P, Chung EM, Emes RD, O'Callaghan C, UK10K., Bouvagnet P, Mitchison HM
Human molecular genetics 2014 Jul 1;23(13):3362-74

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Loss-of-function mutations in RSPH1 cause primary ciliary dyskinesia with central-complex and radial-spoke defects.

Kott E, Legendre M, Copin B, Papon JF, Dastot-Le Moal F, Montantin G, Duquesnoy P, Piterboth W, Amram D, Bassinet L, Beucher J, Beydon N, Deneuville E, Houdouin V, Journel H, Just J, Nathan N, Tamalet A, Collot N, Jeanson L, Le Gouez M, Vallette B, Vojtek AM, Epaud R, Coste A, Clement A, Housset B, Louis B, Escudier E, Amselem S
American journal of human genetics 2013 Sep 5;93(3):561-70

Immunohistochemistry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: TSGA2 Antibody [NBP1-89839] - Staining of human fallopian tube shows high expression.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: TSGA2 Antibody [NBP1-89839] - Staining of human placenta shows low expression as expected.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: TSGA2 Antibody [NBP1-89839] - Staining in human fallopian tube and placenta tissues using anti-RSPH1 antibody. Corresponding RSPH1 RNA-seq data are presented for the same tissues.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: TSGA2 Antibody [NBP1-89839] - Staining of human cerebral cortex, fallopian tube, placenta and testis using Anti-RSPH1 antibody NBP1-89839 (A) shows similar protein distribution across tissues to independent antibody NBP1-89840 (B).

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: TSGA2 Antibody [NBP1-89839] - Staining of human testis.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: TSGA2 Antibody [NBP1-89839] - Staining of human cerebral cortex.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: TSGA2 Antibody [NBP1-89839] - Staining of human placenta using Anti-RSPH1 antibody NBP1-89839.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: TSGA2 Antibody [NBP1-89839] - Staining of human fallopian tube using Anti-RSPH1 antibody NBP1-89839.