MYO1C

This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19. [provided by RefSeq, Jul 2008]

Description

Myosin IC

Tissue specificity

Low tissue specificity

Subcell location

Nuclear bodies, Plasma membrane

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters

Chromosome

17 (1464186 - 1492686)

Ensembl ID

ENSG00000197879  (ver. 103.38)

Orthologs

Mouse Myo1c: ENSMUSG00000017774

UniProt

O00159

neXtProt

NX_O00159

Human splice variants
Mouse splice variants

Protein structure