FNab05034

antibody from FineTest Biotech

Targeting: MBD2

Western blot

ELISA

Antibody data

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Validation data

Product number: FNab05034 - Provider product page
Provider: FineTest Biotech
Product name: MBD2 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
Reactivity: Human, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: methyl-CpG binding domain protein 2
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

MBD2 protein structure - FNab05034 shown in red.