BS2331

antibody from Bioworld Technology, Inc
Targeting: CCAR2 DBC-1, DBC1, KIAA1967, NET35
Provider product page for BS2331

Antibody data

Product number
BS2331 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS2331, RRID:AB_1662201
Product name
DBC 1 (Q455) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 420-476 of Human DBC-1.
Description
DBC1 (deleted in bladder cancer 1), also known as DBCCR1 or FAM5A, is a novel 761 amino acid cytoplasmic protein that functions as an essential regulator of tumorigenesis and mediates expression of components of the plasminogen pathway. Evolutionarily conserved and highly expressed in brain, DBC1 is found at weak levels in small intestine, lung, kidney, testis, prostate, thymus, heart and kidney. DBC1 contains one MACPF domain, belongs to the FAM5 family and inhibits cell proliferation at the G1S transition via negative regulation. DBC1 contains a 5' CpG island that, when hypermethylated, leads to silencing in 50 percent of bladder cancer cell lines.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CCAR2 protein structure - BS2331 shown in red.