BS7951

antibody from Bioworld Technology, Inc

Targeting: LY86 dJ80N2.1, MD-1

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS7951

Provider

Bioworld Technology, Inc

Product name

LY86 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human LY86.

Description

RP105 (CD180) was originally discovered as a mouse B cell surface molecule that transmits an activation signal. This signal leads to resistance against irradiation-induced apoptosis and massive B cell proliferation. RP105 is associated with another molecule, MD-1, which has an important role in the cell surface expression of RP105. MD-1, also known as lymphocyte antigen 68 and RP105 associated protein, associates with and regulates the cell surface expression of RP105. RP105/MD-1 constitutes an LPS-signaling complex on B cells and, like MD-2, enhances the LPS signaling via TLR4. MD-1 contains 162 amino acids and has a predicted 19 amino acid signal peptide and 2 N-glycosylation sites. MD-1 is highly expressed in B cells, monocytes and tonsil, and is localized on the surface of cells despite its lack of a transmembrane region.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.