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- Antigen structure
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- Product number
- A15752 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD264 (TRAIL-R4) Monoclonal Antibody (TRAIL-R4-01), FITC
- Antibody type
- Monoclonal
- Antigen
- Other
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Antibody clone number
- TRAIL-R4-01
- Vial size
- 100 µg
- Concentration
- 0.1 mg/mL
- Storage
- 4° C, store in dark
Submitted references HTNV Sensitizes Host Toward TRAIL-Mediated Apoptosis-A Pivotal Anti-hantaviral Role of TRAIL.
Toxicological effects of bioactive peptide fractions obtained from Bothrops jararaca snake venom on the structure and function of mouse seminiferous epithelium.
Chen QZ, Wang X, Luo F, Li N, Zhu N, Lu S, Zan YX, Zhong CJ, Wang MR, Hu HT, Zhang YZ, Xiong HR, Hou W
Frontiers in immunology 2020;11:1072
Frontiers in immunology 2020;11:1072
Toxicological effects of bioactive peptide fractions obtained from Bothrops jararaca snake venom on the structure and function of mouse seminiferous epithelium.
Alberto-Silva C, Franzin CS, Gilio JM, Bonfim RS, Querobino SM
The journal of venomous animals and toxins including tropical diseases 2020 Jun 22;26:e20200007
The journal of venomous animals and toxins including tropical diseases 2020 Jun 22;26:e20200007
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 4. Effects of LMWF on the distribution of claudin-1 in the seminiferous epithelium. ( A ) Non-specific staining was detected only in the basal and adluminal compartments of seminiferous epithelium of control sections - negative control. ( B - C ) Immunohistochemical staining of RT transverse cross-sections treated with 0.91% w/v NaCl. ( D - F ) Immunostaining of claudin-1 following treatment with LMWF demonstrated no difference in the distribution of claudin-1 when compared to the control group treated with 0.91% w/v NaCl. Hematoxylin was used for counterstaining.
- Conjugate
- Green dye
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 1 HTNV induces TRAIL-dependent apoptosis in primary HUVECs. HUVECs were infected with/without HTNV 76-118 (MOI = 1) for 2 h and followed by qRT-PCR and Western blot at different days to measure TRAIL-related apoptosis factors. (A) HTNV S, TRAIL, DcR1, DcR2, caspase-8, and caspase-3 mRNA in HTNV-infected HUVECs. (B) HTNV NP and TRAIL-related apoptosis proteins expression in HTNV-infected HUVECs. (C) TRAIL-DR4/DR5 and (D) caspase-9 mRNA and protein expression during HTNV infection. The mRNA results shown are the average of three replicates; values represent the mean +- SD ( * p < 0.05; ** p < 0.01; *** p < 0.001). Proteins were quantified using carestream software and compared with the normal control group of 2 dpi. Data were from one of three experiments with similar results. The numbers represented the relative density of the bands relative to the corresponding control. (E) Histogram showing DR4, DR5, DcR1, and DcR2 surface expression on HTNV-infected and uninfected HUVECs at 2 dpi. White histograms indicate fluorescent labeling with receptor-specific monoclonal antibodies, and gray histograms show background labeling with isotype-matched control antibody in the same group. The experiment was repeated three times and data represent one of three separate experiments. (F) Data showing the MFI of DR4, DR5, DcR1, and DcR2 surface expression on HTNV-infected relative to the uninfected HUVECs at 2 dpi. The MFI of TRAIL receptors was assessed by FlowJo software. The experimen
- Conjugate
- Green dye
