ABIN499762

antibody from antibodies-online

Targeting: TNFRSF10A Apo2, CD261, DR4, TRAILR-1, TRAILR1

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN499762

Provider

antibodies-online

Product name

anti-Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A) (C-Term) antibody

Antibody type

Polyclonal

Antigen

Human DR4 (C-Terminus) Peptide (AP30299CP-N)

Description

DEAE

Reactivity

Human

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

0.1 mg

Storage

Store the antibody undiluted at 2-8°C.

References

Submitted references

TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB.

Schneider P, Thome M, Burns K, Bodmer JL, Hofmann K, Kataoka T, Holler N, Tschopp J
Immunity 1997 Dec;7(6):831-6

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The receptor for the cytotoxic ligand TRAIL.

Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM
Science (New York, N.Y.) 1997 Apr 4;276(5309):111-3

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Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family.

Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A
The Journal of biological chemistry 1996 May 31;271(22):12687-90

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Identification and characterization of a new member of the TNF family that induces apoptosis.

Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, Sutherland GR, Smith TD, Rauch C, Smith CA
Immunity 1995 Dec;3(6):673-82

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of DR4 in HeLa total cell lysate with AP30299PU-N DR4 antibody at 1/500 dilution.

Immunocytochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Immunocytochemistry of DR4 in Jurkat cells with AP30299PU-N DR4 antibody at 10 ?g/ml.