AMM01749G

antibody from Leading Biology

Targeting: TNFRSF10A Apo2, CD261, DR4, TRAILR-1, TRAILR1

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM01749G

Provider

Leading Biology

Product name

TNFRSF10A / DR4 Antibody (clone 32A242)

Antibody type

Monoclonal

Description

Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF- kappa-B.

Reactivity

Human

Host

Mouse

Antibody clone number

32A242

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.