GTX28414

antibody from GeneTex

Targeting: TNFRSF10A Apo2, CD261, DR4, TRAILR-1, TRAILR1

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

GTX28414

Provider

GeneTex

Proper citation

GeneTex Cat#GTX28414, RRID:AB_367920

Product name

DR4 antibody

Antibody type

Polyclonal

Reactivity

Human

Host

Rabbit

References

Submitted references

The TRAIL receptor agonist drozitumab targets basal B triple-negative breast cancer cells that express vimentin and Axl.

Dine JL, O'Sullivan CC, Voeller D, Greer YE, Chavez KJ, Conway CM, Sinclair S, Stone B, Amiri-Kordestani L, Merchant AS, Hewitt SM, Steinberg SM, Swain SM, Lipkowitz S
Breast cancer research and treatment 2016 Jan;155(2):235-51

---

Luteolin sensitizes human 786-O renal cell carcinoma cells to TRAIL-induced apoptosis.

Ou YC, Li JR, Kuan YH, Raung SL, Wang CC, Hung YY, Pan PH, Lu HC, Chen CJ
Life sciences 2014 Apr 1;100(2):110-7

---

WEE1 inhibition sensitizes basal breast cancer cells to TRAIL-induced apoptosis.

Garimella SV, Rocca A, Lipkowitz S
Molecular cancer research : MCR 2012 Jan;10(1):75-85

Western blot

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Western blot analysis of DR4 in HeLa cell lysate with DR4 antibody (GTX28414) at 1μg/ml.

Immunocytochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Immunocytochemical staining of DR4 in Jurkat cells with DR4 antibody (GTX28414) at 10μg/ml.

Immunohistochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

Immunohistochemistry of DR4 in human spleen tissue with DR4 antibody at 5 μg/mL.