ZNF274

This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq, Jul 2008]

Description

Zinc finger protein 274

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Centrosome

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

19 (58183029 - 58213562)

Ensembl ID

ENSG00000171606  (ver. 103.38)

Orthologs

-

UniProt

Q96GC6

neXtProt

NX_Q96GC6

Human splice variants

Protein structure