AF1334

antibody from Novus Biologicals

Targeting: IGFBP7 FSTL2, IGFBP-7, MAC25, PSF

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

AF1334

Provider

Novus Biologicals

Product name

Goat Polyclonal IGFBP-rp1/IGFBP-7 Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects human IGFBP-rp1 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) IGFBP-L1, rhIGFBP-rp10 and recombinant mouse IGFBP-7 is observed.

Reactivity

Human

Host

Goat

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons.

Riessland M, Kolisnyk B, Kim TW, Cheng J, Ni J, Pearson JA, Park EJ, Dam K, Acehan D, Ramos-Espiritu LS, Wang W, Zhang J, Shim JW, Ciceri G, Brichta L, Studer L, Greengard P
Cell stem cell 2019 Oct 3;25(4):514-530.e8

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IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor-stroma interaction.

Rupp C, Scherzer M, Rudisch A, Unger C, Haslinger C, Schweifer N, Artaker M, Nivarthi H, Moriggl R, Hengstschläger M, Kerjaschki D, Sommergruber W, Dolznig H, Garin-Chesa P
Oncogene 2015 Feb 12;34(7):815-25

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Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis.

Cheriyan VT, Wang Y, Muthu M, Jamal S, Chen D, Yang H, Polin LA, Tarca AL, Pass HI, Dou QP, Sharma S, Wali A, Rishi AK
PloS one 2014;9(4):e93711

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Regulation of human skin pigmentation in situ by repetitive UV exposure: molecular characterization of responses to UVA and/or UVB.

Choi W, Miyamura Y, Wolber R, Smuda C, Reinhold W, Liu H, Kolbe L, Hearing VJ
The Journal of investigative dermatology 2010 Jun;130(6):1685-96

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Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling.

Pen A, Moreno MJ, Durocher Y, Deb-Rinker P, Stanimirovic DB
Oncogene 2008 Nov 20;27(54):6834-44

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Insulin-like growth factor binding protein 7 mediates glioma cell growth and migration.

Jiang W, Xiang C, Cazacu S, Brodie C, Mikkelsen T
Neoplasia (New York, N.Y.) 2008 Dec;10(12):1335-42

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Insulin-like growth factor binding protein 7 mediates glioma cell growth and migration.

Jiang W, Xiang C, Cazacu S, Brodie C, Mikkelsen T
Neoplasia (New York, N.Y.) 2008 Dec;10(12):1335-42

Western blot

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Detection of Human IGFBP-rp1/IGFBP-7 by Western Blot. Detection of Human IGFBP-rp1/IGFBP-7 by Western Blot.

Immunohistochemistry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

IGFBP-rp1/IGFBP-7 in Human Pancreas. IGFBP-rp1/IGFBP-7 in Human Pancreas.