BS3453

antibody from Bioworld Technology, Inc
Targeting: ITGAE CD103, HUMINAE
Provider product page for BS3453

Antibody data

Product number
BS3453 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Integrin Ï«E (L180) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 150-200 of Human Integrin Ï«E.
Description
Integrins are heterodimers composed of noncovalently associated transmembrane Ï« and ÉÇ subunits. The 16Ï« and 8ÉÇ subunits heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent Integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of Integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ITGAE protein structure - BS3453 shown in red.