Tissue expression
Cell line expression
Protein structure
MAP2K7
Mitogen-activated protein kinase kinase 7Jnkk2, MKK7, PRKMK7
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Top validated antibodies |
|||||
| antibodies-online | 3 references | Monoclonal |
|
||
| LSBio | Monoclonal |
|
|||
| OriGene | Monoclonal |
|
|||
| Acris Antibodies GmbH | Monoclonal |
|
|||
| GeneTex | Monoclonal |
|
|||