Tissue expression
Cell line expression
Protein structure
NCOR1
Nuclear receptor corepressor 1hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. [provided by RefSeq, Jun 2010]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
23 references | Polyclonal |
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GeneTex | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
1 references | Monoclonal |
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Proteintech Group | ![]() |
7 references | Polyclonal |
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