Antibody data
- Antibody Data
- Antigen structure
- References [62]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
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- Product number
- 14550-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14550-1-AP, RRID:AB_2223933
- Product name
- AFP antibody
- Antibody type
- Polyclonal
- Description
- AFP antibody (Cat. #14550-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ESRRB Facilitates the Conversion of Trophoblast-Like Stem Cells From Induced Pluripotent Stem Cells by Directly Regulating CDX2.
Glycogen accumulation and phase separation drives liver tumor initiation.
GP73-mediated secretion of AFP and GP73 promotes proliferation and metastasis of hepatocellular carcinoma cells.
Establishment of an induced pluripotent stem cell line (ZZUPMCi001-A) derived from peripheral blood mononuclear cells in a patient with type 1 Waardenburg syndrome.
A Combined Model of Human iPSC-Derived Liver Organoids and Hepatocytes Reveals Ferroptosis in DGUOK Mutant mtDNA Depletion Syndrome.
Novel Technique for Retinal Nerve Cell Regeneration with Electrophysiological Functions Using Human Iris-Derived iPS Cells.
Icaritin promotes apoptosis and inhibits proliferation by down-regulating AFP gene expression in hepatocellular carcinoma.
Whole-exome sequencing of alpha-fetoprotein producing gastric carcinoma reveals genomic profile and therapeutic targets.
Rebalancing TGF-β/Smad7 signaling via Compound kushen injection in hepatic stellate cells protects against liver fibrosis and hepatocarcinogenesis.
Selective eradication of pluripotent stem cells by inhibiting DHODH activity.
Chemerin reverses the malignant phenotype and induces differentiation of human hepatoma SMMC7721 cells.
Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma.
Generation of combined hepatocellular-cholangiocarcinoma through transdifferentiation and dedifferentiation in p53-knockout mice.
Modified CRISPR/Cas9 mediated generation of two MKK7 knockout human embryonic stem cell lines.
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Alpha-Fetoprotein Regulates the Expression of Immune-Related Proteins through the NF-κB (P65) Pathway in Hepatocellular Carcinoma Cells.
The clinicopathological features and prognosis of serum AFP positive gastric cancer: a report of 16 cases.
All-trans-retinoic acid inhibits the malignant behaviors of hepatocarcinoma cells by regulating autophagy.
Generation and characterization of a human iPSC line derived from congenital clubfoot amniotic fluid cells.
Hepatitis B virus X protein upregulates alpha-fetoprotein to promote hepatocellular carcinoma by targeting miR-1236 and miR-329.
An analysis of monocytes and dendritic cells differentiated from human peripheral blood monocyte-derived induced pluripotent stem cells.
SALL4 is a useful marker for pediatric yolk sac tumors.
Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient-derived organoids.
Acetylation of alpha-fetoprotein promotes hepatocellular carcinoma progression.
The role of bone marrow-derived cells in the origin of liver cancer revealed by single-cell sequencing.
Establishment of a control induced pluripotent stem cell line SMBCi006-A from a healthy male donor.
Alpha-fetoprotein accelerates the progression of hepatocellular carcinoma by promoting Bcl-2 gene expression through an RA-RAR signalling pathway.
Inhibition of protein kinase D by CID755673 promotes maintenance of the pluripotency of embryonic stem cells.
RACK1 Promotes Self-Renewal and Chemoresistance of Cancer Stem Cells in Human Hepatocellular Carcinoma through Stabilizing Nanog.
Alarmin augments the antitumor immunity of lentiviral vaccine in ectopic, orthotopic and autochthonous hepatocellular carcinoma mice.
Peri-tumor fibroblasts promote tumorigenesis and metastasis of hepatocellular carcinoma via Interleukin6/STAT3 signaling pathway.
Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations.
TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma.
Au@SiO2@CuInS2-ZnS/Anti-AFP fluorescent probe improves HCC cell labeling.
Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes.
Generation and Characterization of Induced Pluripotent Stem Cells from Mononuclear Cells in Schizophrenic Patients.
Breakdown of adaptive immunotolerance induces hepatocellular carcinoma in HBsAg-tg mice.
Anticancer effects of echinacoside in hepatocellular carcinoma mouse model and HepG2 cells.
Diet-induced hepatic steatosis activates Ras to promote hepatocarcinogenesis via CPT1α.
Signal transducer and activator of transcription 3 promotes the Warburg effect possibly by inducing pyruvate kinase M2 phosphorylation in liver precancerous lesions.
hPCL3s Promotes Hepatocellular Carcinoma Metastasis by Activating β-Catenin Signaling.
HCC-derived exosomes elicit HCC progression and recurrence by epithelial-mesenchymal transition through MAPK/ERK signalling pathway.
HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis.
Preparation of Induced Pluripotent Stem Cells Using Human Peripheral Blood Monocytes.
Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice.
Oncogenic Determination of a Broad Spectrum of Phenotypes of Hepatocyte-Derived Mouse Liver Tumors.
Transcriptome Analysis of WHV/c-myc Transgenic Mice Implicates Cytochrome P450 Enzyme 17A1 as a Promising Biomarker for Hepatocellular Carcinoma.
A fluorescent ELISA based on the enzyme-triggered synthesis of poly(thymine)-templated copper nanoparticles.
PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency.
NOX1 supports the metabolic remodeling of HepG2 cells.
PRDM14 maintains pluripotency of embryonic stem cells through TET-mediated active DNA demethylation.
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.
Animal and cellular models of hepatocellular carcinoma bone metastasis: establishment and characterisation.
Aberrant expression of claudin-4 and -7 in hepatocytes in the cirrhotic human liver.
Accelerated hepatocellular carcinoma development in CUL4B transgenic mice.
Differential reactivation of fetal/neonatal genes in mouse liver tumors induced in cirrhotic and non-cirrhotic conditions.
Expression and activation of EGFR and STAT3 during the multistage carcinogenesis of intrahepatic cholangiocarcinoma induced by 3'-methyl-4 dimethylaminoazobenzene in rats.
Revival, characterization, and hepatitis B virus infection of cryopreserved human fetal hepatocytes.
Long-term maintenance of human fetal hepatocytes and prolonged susceptibility to HBV infection by co-culture with non-parenchymal cells.
Stage specific reprogramming of mouse embryo liver cells to a beta cell-like phenotype.
Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains.
Recovery of mature hepatocytic phenotype following bile ductular transdifferentiation of rat hepatocytes in vitro.
Yu S, Zhang R, Shen Q, Zhu Z, Zhang J, Wu X, Zhao W, Li N, Yang F, Wei H, Hua J
Frontiers in cell and developmental biology 2021;9:712224
Frontiers in cell and developmental biology 2021;9:712224
Glycogen accumulation and phase separation drives liver tumor initiation.
Liu Q, Li J, Zhang W, Xiao C, Zhang S, Nian C, Li J, Su D, Chen L, Zhao Q, Shao H, Zhao H, Chen Q, Li Y, Geng J, Hong L, Lin S, Wu Q, Deng X, Ke R, Ding J, Johnson RL, Liu X, Chen L, Zhou D
Cell 2021 Oct 28;184(22):5559-5576.e19
Cell 2021 Oct 28;184(22):5559-5576.e19
GP73-mediated secretion of AFP and GP73 promotes proliferation and metastasis of hepatocellular carcinoma cells.
Liu Y, Wang J, Yang R, Cheng Y, Zhou Y, Li H, Jiang W, Zhang X
Oncogenesis 2021 Oct 14;10(10):69
Oncogenesis 2021 Oct 14;10(10):69
Establishment of an induced pluripotent stem cell line (ZZUPMCi001-A) derived from peripheral blood mononuclear cells in a patient with type 1 Waardenburg syndrome.
Wang X, Zhang S, Hu S, Xu H, Zhang Q, Tang W
Stem cell research 2021 Nov 25;57:102606
Stem cell research 2021 Nov 25;57:102606
A Combined Model of Human iPSC-Derived Liver Organoids and Hepatocytes Reveals Ferroptosis in DGUOK Mutant mtDNA Depletion Syndrome.
Guo J, Duan L, He X, Li S, Wu Y, Xiang G, Bao F, Yang L, Shi H, Gao M, Zheng L, Hu H, Liu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(10):2004680
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 May;8(10):2004680
Novel Technique for Retinal Nerve Cell Regeneration with Electrophysiological Functions Using Human Iris-Derived iPS Cells.
Yamamoto N, Hiramatsu N, Ohkuma M, Hatsusaka N, Takeda S, Nagai N, Miyachi EI, Kondo M, Imaizumi K, Horiguchi M, Kubo E, Sasaki H
Cells 2021 Mar 28;10(4)
Cells 2021 Mar 28;10(4)
Icaritin promotes apoptosis and inhibits proliferation by down-regulating AFP gene expression in hepatocellular carcinoma.
Li H, Liu Y, Jiang W, Xue J, Cheng Y, Wang J, Yang R, Zhang X
BMC cancer 2021 Mar 25;21(1):318
BMC cancer 2021 Mar 25;21(1):318
Whole-exome sequencing of alpha-fetoprotein producing gastric carcinoma reveals genomic profile and therapeutic targets.
Lu J, Ding Y, Chen Y, Jiang J, Chen Y, Huang Y, Wu M, Li C, Kong M, Zhao W, Wang H, Zhang J, Li Z, Lu Y, Yu X, Jin K, Zhou D, Zhou T, Teng F, Zhang H, Zhou Z, Wang H, Teng L
Nature communications 2021 Jun 24;12(1):3946
Nature communications 2021 Jun 24;12(1):3946
Rebalancing TGF-β/Smad7 signaling via Compound kushen injection in hepatic stellate cells protects against liver fibrosis and hepatocarcinogenesis.
Yang Y, Sun M, Li W, Liu C, Jiang Z, Gu P, Li J, Wang W, You R, Ba Q, Li X, Wang H
Clinical and translational medicine 2021 Jul;11(7):e410
Clinical and translational medicine 2021 Jul;11(7):e410
Selective eradication of pluripotent stem cells by inhibiting DHODH activity.
Kondo T
Stem cells (Dayton, Ohio) 2021 Jan;39(1):33-42
Stem cells (Dayton, Ohio) 2021 Jan;39(1):33-42
Chemerin reverses the malignant phenotype and induces differentiation of human hepatoma SMMC7721 cells.
Li M, Sun P, Dong K, Xin Y, TaiLulu A, Li Q, Sun J, Peng M, Shi P
Archives of pharmacal research 2021 Feb;44(2):194-204
Archives of pharmacal research 2021 Feb;44(2):194-204
Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma.
Cheng W, Li HL, Xi SY, Zhang XF, Zhu Y, Le Xing, Mo YX, Li MM, Kong FE, Zhu WJ, Chen XG, Cui HQ, Cao ZM, Gong YF, Tang YQ, Zhang Y, Guan XY, Ma NF, Liu M
Nature communications 2021 Dec 8;12(1):7142
Nature communications 2021 Dec 8;12(1):7142
Generation of combined hepatocellular-cholangiocarcinoma through transdifferentiation and dedifferentiation in p53-knockout mice.
Liu Y, Xin B, Yamamoto M, Goto M, Ooshio T, Kamikokura Y, Tanaka H, Meng L, Okada Y, Mizukami Y, Nishikawa Y
Cancer science 2021 Aug;112(8):3111-3124
Cancer science 2021 Aug;112(8):3111-3124
Modified CRISPR/Cas9 mediated generation of two MKK7 knockout human embryonic stem cell lines.
Sims CHC, Autio MI, Buskin A, Cheung C, Heer R, Foo RSY, Wang X
Stem cell research 2021 Apr;52:102238
Stem cell research 2021 Apr;52:102238
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Cao Z, Cheng Y, Wang J, Liu Y, Yang R, Jiang W, Li H, Zhang X
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Alpha-Fetoprotein Regulates the Expression of Immune-Related Proteins through the NF-κB (P65) Pathway in Hepatocellular Carcinoma Cells.
Li QT, Qiu MJ, Yang SL, Fang X, He XX, Wang MM, Li YN, Xiong ZF, Huang S
Journal of oncology 2020;2020:9327512
Journal of oncology 2020;2020:9327512
The clinicopathological features and prognosis of serum AFP positive gastric cancer: a report of 16 cases.
Liu D, Li B, Yan B, Liu L, Jia Y, Wang Y, Ma X, Yang F
International journal of clinical and experimental pathology 2020;13(9):2439-2446
International journal of clinical and experimental pathology 2020;13(9):2439-2446
All-trans-retinoic acid inhibits the malignant behaviors of hepatocarcinoma cells by regulating autophagy.
Fang S, Hu C, Xu L, Cui J, Tao L, Gong M, Wang Y, He Y, He T, Bi Y
American journal of translational research 2020;12(10):6793-6810
American journal of translational research 2020;12(10):6793-6810
Generation and characterization of a human iPSC line derived from congenital clubfoot amniotic fluid cells.
Wang J, Cui Y, Xing K, Luan J, Han J
Stem cell research 2020 Mar;43:101712
Stem cell research 2020 Mar;43:101712
Hepatitis B virus X protein upregulates alpha-fetoprotein to promote hepatocellular carcinoma by targeting miR-1236 and miR-329.
Zhang C, Liu P, Zhang C
Journal of cellular biochemistry 2020 Mar;121(3):2489-2499
Journal of cellular biochemistry 2020 Mar;121(3):2489-2499
An analysis of monocytes and dendritic cells differentiated from human peripheral blood monocyte-derived induced pluripotent stem cells.
Hiramatsu N, Yamamoto N, Isogai S, Onouchi T, Hirayama M, Maeda S, Ina T, Kondo M, Imaizumi K
Medical molecular morphology 2020 Jun;53(2):63-72
Medical molecular morphology 2020 Jun;53(2):63-72
SALL4 is a useful marker for pediatric yolk sac tumors.
Wu P, Luo R, Sun B, Zhao J, Xu Q, Feng S, Chen X, Wang C
Pediatric surgery international 2020 Jun;36(6):727-734
Pediatric surgery international 2020 Jun;36(6):727-734
Hedgehog signaling promotes sorafenib resistance in hepatocellular carcinoma patient-derived organoids.
Wang S, Wang Y, Xun X, Zhang C, Xiang X, Cheng Q, Hu S, Li Z, Zhu J
Journal of experimental & clinical cancer research : CR 2020 Jan 28;39(1):22
Journal of experimental & clinical cancer research : CR 2020 Jan 28;39(1):22
Acetylation of alpha-fetoprotein promotes hepatocellular carcinoma progression.
Xue J, Cao Z, Cheng Y, Wang J, Liu Y, Yang R, Li H, Jiang W, Li G, Zhao W, Zhang X
Cancer letters 2020 Feb 28;471:12-26
Cancer letters 2020 Feb 28;471:12-26
The role of bone marrow-derived cells in the origin of liver cancer revealed by single-cell sequencing.
Chen L, Yi X, Guo P, Guo H, Chen Z, Hou C, Qi L, Wang Y, Li C, Liu P, Liu Y, Xu Y, Zhang N
Cancer biology & medicine 2020 Feb 15;17(1):142-153
Cancer biology & medicine 2020 Feb 15;17(1):142-153
Establishment of a control induced pluripotent stem cell line SMBCi006-A from a healthy male donor.
Shi L, Cui Y, Zhang G, Zhou X, Luan J, Han J
Stem cell research 2020 Dec;49:102025
Stem cell research 2020 Dec;49:102025
Alpha-fetoprotein accelerates the progression of hepatocellular carcinoma by promoting Bcl-2 gene expression through an RA-RAR signalling pathway.
Zhang C, Zhang J, Wang J, Yan Y, Zhang C
Journal of cellular and molecular medicine 2020 Dec;24(23):13804-13812
Journal of cellular and molecular medicine 2020 Dec;24(23):13804-13812
Inhibition of protein kinase D by CID755673 promotes maintenance of the pluripotency of embryonic stem cells.
Zhu Z, Zhang Y, Wang X, Wang X, Ye SD
Development (Cambridge, England) 2020 Aug 24;147(16)
Development (Cambridge, England) 2020 Aug 24;147(16)
RACK1 Promotes Self-Renewal and Chemoresistance of Cancer Stem Cells in Human Hepatocellular Carcinoma through Stabilizing Nanog.
Cao J, Zhao M, Liu J, Zhang X, Pei Y, Wang J, Yang X, Shen B, Zhang J
Theranostics 2019;9(3):811-828
Theranostics 2019;9(3):811-828
Alarmin augments the antitumor immunity of lentiviral vaccine in ectopic, orthotopic and autochthonous hepatocellular carcinoma mice.
Liu Z, Lu Z, Jing R, Zuo B, Gao X, Han G, Qi H, Wu L, Liu Y, Yin H
Theranostics 2019;9(14):4006-4018
Theranostics 2019;9(14):4006-4018
Peri-tumor fibroblasts promote tumorigenesis and metastasis of hepatocellular carcinoma via Interleukin6/STAT3 signaling pathway.
Zhao Z, Xiong S, Wang R, Li Y, Wang X, Wang Y, Bai S, Chen W, Zhao Y, Cheng B
Cancer management and research 2019;11:2889-2901
Cancer management and research 2019;11:2889-2901
Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations.
Watanabe K, Yamamoto M, Xin B, Ooshio T, Goto M, Fujii K, Liu Y, Okada Y, Furukawa H, Nishikawa Y
Hepatology communications 2019 May;3(5):697-715
Hepatology communications 2019 May;3(5):697-715
TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma.
Zhang J, Liu P, Tao J, Wang P, Zhang Y, Song X, Che L, Sumazin P, Ribback S, Kiss A, Schaff Z, Cigliano A, Dombrowski F, Cossu C, Pascale RM, Calvisi DF, Monga SP, Chen X
The American journal of pathology 2019 May;189(5):1077-1090
The American journal of pathology 2019 May;189(5):1077-1090
Au@SiO2@CuInS2-ZnS/Anti-AFP fluorescent probe improves HCC cell labeling.
Dai YW, Zhu LX, Zhang Y, Wang SH, Chen K, Jiang TT, Xu XL, Geng XP
Hepatobiliary & pancreatic diseases international : HBPD INT 2019 Jun;18(3):266-272
Hepatobiliary & pancreatic diseases international : HBPD INT 2019 Jun;18(3):266-272
Genomic and Transcriptomic Profiling of Combined Hepatocellular and Intrahepatic Cholangiocarcinoma Reveals Distinct Molecular Subtypes.
Xue R, Chen L, Zhang C, Fujita M, Li R, Yan SM, Ong CK, Liao X, Gao Q, Sasagawa S, Li Y, Wang J, Guo H, Huang QT, Zhong Q, Tan J, Qi L, Gong W, Hong Z, Li M, Zhao J, Peng T, Lu Y, Lim KHT, Boot A, Ono A, Chayama K, Zhang Z, Rozen SG, Teh BT, Wang XW, Nakagawa H, Zeng MS, Bai F, Zhang N
Cancer cell 2019 Jun 10;35(6):932-947.e8
Cancer cell 2019 Jun 10;35(6):932-947.e8
Generation and Characterization of Induced Pluripotent Stem Cells from Mononuclear Cells in Schizophrenic Patients.
Liu Q, Du J, Fan J, Li W, Guo W, Feng H, Lin J
Cell journal 2019 Jul;21(2):161-168
Cell journal 2019 Jul;21(2):161-168
Breakdown of adaptive immunotolerance induces hepatocellular carcinoma in HBsAg-tg mice.
Zong L, Peng H, Sun C, Li F, Zheng M, Chen Y, Wei H, Sun R, Tian Z
Nature communications 2019 Jan 15;10(1):221
Nature communications 2019 Jan 15;10(1):221
Anticancer effects of echinacoside in hepatocellular carcinoma mouse model and HepG2 cells.
Ye Y, Song Y, Zhuang J, Wang G, Ni J, Xia W
Journal of cellular physiology 2019 Feb;234(2):1880-1888
Journal of cellular physiology 2019 Feb;234(2):1880-1888
Diet-induced hepatic steatosis activates Ras to promote hepatocarcinogenesis via CPT1α.
Xu A, Wang B, Fu J, Qin W, Yu T, Yang Z, Lu Q, Chen J, Chen Y, Wang H
Cancer letters 2019 Feb 1;442:40-52
Cancer letters 2019 Feb 1;442:40-52
Signal transducer and activator of transcription 3 promotes the Warburg effect possibly by inducing pyruvate kinase M2 phosphorylation in liver precancerous lesions.
Bi YH, Han WQ, Li RF, Wang YJ, Du ZS, Wang XJ, Jiang Y
World journal of gastroenterology 2019 Apr 28;25(16):1936-1949
World journal of gastroenterology 2019 Apr 28;25(16):1936-1949
hPCL3s Promotes Hepatocellular Carcinoma Metastasis by Activating β-Catenin Signaling.
Cai Z, Qian ZY, Jiang H, Ma N, Li Z, Liu LY, Ren XX, Shang YR, Wang JJ, Li JJ, Liu DP, Zhang XP, Feng D, Ni QZ, Feng YY, Li N, Zhou XY, Wang X, Bao Y, Zhang XL, Deng YZ, Xie D
Cancer research 2018 May 15;78(10):2536-2549
Cancer research 2018 May 15;78(10):2536-2549
HCC-derived exosomes elicit HCC progression and recurrence by epithelial-mesenchymal transition through MAPK/ERK signalling pathway.
Chen L, Guo P, He Y, Chen Z, Chen L, Luo Y, Qi L, Liu Y, Wu Q, Cui Y, Fang F, Zhang X, Song T, Guo H
Cell death & disease 2018 May 1;9(5):513
Cell death & disease 2018 May 1;9(5):513
HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis.
Hernandez C, Huebener P, Pradere JP, Antoine DJ, Friedman RA, Schwabe RF
The Journal of clinical investigation 2018 Jun 1;128(6):2436-2451
The Journal of clinical investigation 2018 Jun 1;128(6):2436-2451
Preparation of Induced Pluripotent Stem Cells Using Human Peripheral Blood Monocytes.
Isogai S, Yamamoto N, Hiramatsu N, Goto Y, Hayashi M, Kondo M, Imaizumi K
Cellular reprogramming 2018 Dec;20(6):347-355
Cellular reprogramming 2018 Dec;20(6):347-355
Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice.
Nault R, Fader KA, Harkema JR, Zacharewski T
PloS one 2017;12(9):e0184842
PloS one 2017;12(9):e0184842
Oncogenic Determination of a Broad Spectrum of Phenotypes of Hepatocyte-Derived Mouse Liver Tumors.
Yamamoto M, Xin B, Watanabe K, Ooshio T, Fujii K, Chen X, Okada Y, Abe H, Taguchi Y, Miyokawa N, Furukawa H, Nishikawa Y
The American journal of pathology 2017 Dec;187(12):2711-2725
The American journal of pathology 2017 Dec;187(12):2711-2725
Transcriptome Analysis of WHV/c-myc Transgenic Mice Implicates Cytochrome P450 Enzyme 17A1 as a Promising Biomarker for Hepatocellular Carcinoma.
Wang F, Huang J, Zhu Z, Ma X, Cao L, Zhang Y, Chen W, Dong Y
Cancer prevention research (Philadelphia, Pa.) 2016 Sep;9(9):739-49
Cancer prevention research (Philadelphia, Pa.) 2016 Sep;9(9):739-49
A fluorescent ELISA based on the enzyme-triggered synthesis of poly(thymine)-templated copper nanoparticles.
Sun J, Hu T, Xu X, Wang L, Yang X
Nanoscale 2016 Sep 29;8(38):16846-16850
Nanoscale 2016 Sep 29;8(38):16846-16850
PRDM14 Drives OCT3/4 Recruitment via Active Demethylation in the Transition from Primed to Naive Pluripotency.
Okashita N, Suwa Y, Nishimura O, Sakashita N, Kadota M, Nagamatsu G, Kawaguchi M, Kashida H, Nakajima A, Tachibana M, Seki Y
Stem cell reports 2016 Dec 13;7(6):1072-1086
Stem cell reports 2016 Dec 13;7(6):1072-1086
NOX1 supports the metabolic remodeling of HepG2 cells.
Bertram K, Valcu CM, Weitnauer M, Linne U, Görlach A
PloS one 2015;10(3):e0122002
PloS one 2015;10(3):e0122002
PRDM14 maintains pluripotency of embryonic stem cells through TET-mediated active DNA demethylation.
Okashita N, Sakashita N, Ito K, Mitsuya A, Suwa Y, Seki Y
Biochemical and biophysical research communications 2015 Oct 9;466(1):138-45
Biochemical and biophysical research communications 2015 Oct 9;466(1):138-45
Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.
Mu X, Español-Suñer R, Mederacke I, Affò S, Manco R, Sempoux C, Lemaigre FP, Adili A, Yuan D, Weber A, Unger K, Heikenwälder M, Leclercq IA, Schwabe RF
The Journal of clinical investigation 2015 Oct 1;125(10):3891-903
The Journal of clinical investigation 2015 Oct 1;125(10):3891-903
Animal and cellular models of hepatocellular carcinoma bone metastasis: establishment and characterisation.
Hou R, Wang YW, Liang HF, Zhang ZG, Liu ZM, Zhang BH, Zhang BX, Chen XP
Journal of cancer research and clinical oncology 2015 Nov;141(11):1931-43
Journal of cancer research and clinical oncology 2015 Nov;141(11):1931-43
Aberrant expression of claudin-4 and -7 in hepatocytes in the cirrhotic human liver.
Tsujiwaki M, Murata M, Takasawa A, Hiratsuka Y, Fukuda R, Sugimoto K, Ono Y, Nojima M, Tanaka S, Hirata K, Kojima T, Sawada N
Medical molecular morphology 2015 Mar;48(1):33-43
Medical molecular morphology 2015 Mar;48(1):33-43
Accelerated hepatocellular carcinoma development in CUL4B transgenic mice.
Yuan J, Jiang B, Zhang A, Qian Y, Tan H, Gao J, Shao C, Gong Y
Oncotarget 2015 Jun 20;6(17):15209-21
Oncotarget 2015 Jun 20;6(17):15209-21
Differential reactivation of fetal/neonatal genes in mouse liver tumors induced in cirrhotic and non-cirrhotic conditions.
Chen X, Yamamoto M, Fujii K, Nagahama Y, Ooshio T, Xin B, Okada Y, Furukawa H, Nishikawa Y
Cancer science 2015 Aug;106(8):972-81
Cancer science 2015 Aug;106(8):972-81
Expression and activation of EGFR and STAT3 during the multistage carcinogenesis of intrahepatic cholangiocarcinoma induced by 3'-methyl-4 dimethylaminoazobenzene in rats.
Zhang F, Li L, Yang X, Wang B, Zhao J, Lu S, Yu X
Journal of toxicologic pathology 2015 Apr;28(2):79-87
Journal of toxicologic pathology 2015 Apr;28(2):79-87
Revival, characterization, and hepatitis B virus infection of cryopreserved human fetal hepatocytes.
Zhou M, Huang Y, Cheng Z, Zhao F, Li J, Zhi X, Tian X, Sun W, Hu K
Journal of virological methods 2014 Oct;207:29-37
Journal of virological methods 2014 Oct;207:29-37
Long-term maintenance of human fetal hepatocytes and prolonged susceptibility to HBV infection by co-culture with non-parenchymal cells.
Zhou M, Zhao F, Li J, Cheng Z, Tian X, Zhi X, Huang Y, Hu K
Journal of virological methods 2014 Jan;195:185-93
Journal of virological methods 2014 Jan;195:185-93
Stage specific reprogramming of mouse embryo liver cells to a beta cell-like phenotype.
Yang Y, Akinci E, Dutton JR, Banga A, Slack JM
Mechanisms of development 2013 Nov-Dec;130(11-12):602-12
Mechanisms of development 2013 Nov-Dec;130(11-12):602-12
Pleiotropy of glycogen synthase kinase-3 inhibition by CHIR99021 promotes self-renewal of embryonic stem cells from refractory mouse strains.
Ye S, Tan L, Yang R, Fang B, Qu S, Schulze EN, Song H, Ying Q, Li P
PloS one 2012;7(4):e35892
PloS one 2012;7(4):e35892
Recovery of mature hepatocytic phenotype following bile ductular transdifferentiation of rat hepatocytes in vitro.
Sone M, Nishikawa Y, Nagahama Y, Kumagai E, Doi Y, Omori Y, Yoshioka T, Tokairin T, Yoshida M, Sugiyama T, Enomoto K
The American journal of pathology 2012 Dec;181(6):2094-104
The American journal of pathology 2012 Dec;181(6):2094-104
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 14550-1-AP(AFP antibody) at dilution of 1:2000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-AFP (IP:14550-1-AP, 5ug; Detection:14550-1-AP 1:1000) with HepG2 cells lysate 6000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 14550-1-AP(AFP antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AFP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AFP. This antibody recognizes human,mouse,rat antigen. The AFP antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.