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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- MAB5383 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB5383, RRID:AB_10677508
- Product name
- SNCA monoclonal antibody, clone 2A7
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against recombinant SNCA.
- Isotype
- IgG
- Antibody clone number
- 2A7
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references alpha-Synuclein and neuronal cell death.
Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease.
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease.
Cookson MR
Molecular neurodegeneration 2009 Feb 4;4:9
Molecular neurodegeneration 2009 Feb 4;4:9
Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease.
Ibáñez P, Bonnet AM, Débarges B, Lohmann E, Tison F, Pollak P, Agid Y, Dürr A, Brice A
Lancet (London, England) 2004 Sep 25-Oct 1;364(9440):1169-71
Lancet (London, England) 2004 Sep 25-Oct 1;364(9440):1169-71
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease.
Chartier-Harlin MC, Kachergus J, Roumier C, Mouroux V, Douay X, Lincoln S, Levecque C, Larvor L, Andrieux J, Hulihan M, Waucquier N, Defebvre L, Amouyel P, Farrer M, Destée A
Lancet (London, England) 2004 Sep 25-Oct 1;364(9440):1167-9
Lancet (London, England) 2004 Sep 25-Oct 1;364(9440):1167-9
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western Blot of SNCA monoclonal antibody, clone 2A7 (Cat # MAB5383) on recombinant SNCA (left lane) and crude extract of mouse brain (right lane, courtesy Rogan Tinsley, Howard Florey Institute, University of Melbourne).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Mixed neuron-glial cultures stained with SNCA monoclonal antibody, clone 2A7 (Cat # MAB5383), our monoclonal antibody to SNCA (red) and chicken polylclonal antibody to MAP2 (green).The SNCA monoclonal antibody stains vesicular structures the perikarya and processes of the neurons in this image.Note that some of the neuronal perikarya contain much more alpha-synuclein than others.The blue channel shows the localization of DNA.
- Validation comment
- Immunofluorescence
