60003

antibody from STEMCELL Technologies Inc

Targeting: SDC1 CD138, SDC, SYND1, syndecan

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

60003

Provider

STEMCELL Technologies Inc

Product name

Anti-Human CD138 (Syndecan-1) Antibody, Clone MI15

Antibody type

Monoclonal

Description

The MI15 antibody reacts with an extracellular epitope on CD138 (Syndecan-1), an ~85 - 95 kDa type 1 transmembrane glycoprotein expressed on the surface of pre-B cells, immature B cells, and normal and malignant plasma cells (but not mature circulating B cells), as well as on non-hematopoietic cells such as embryonic mesenchymal cells, endothelial, epithelial and neural cells. CD138 expression is used as a diagnostic marker for several types of tumors. CD138 is thought to act primarily as a receptor that modulates cell proliferation, cell migration and cell-matrix associations by linking the extracellular matrix to the cytoskeleton. Heparin sulfate and chondroitin sulfate moieties attached to CD138 associate with several proteins, including collagens, fibronectin, tenascin, thrombospondin and certain cytokines. The MI15 antibody recognizes a different epitope than that of the clone DL-101 anti-CD138 antibody but blocks binding of clone B-B4.

Reactivity

Human

Isotype

IgG

Vial size

100 µg

Storage

2 - 8°C