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Protein structure
SDC1
Syndecan 1CD138, SDC, SYND1, syndecan
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| antibodies-online |  ABIN1724936 |
2 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| Invitrogen Antibodies | 36-2900 |
18 references | Polyclonal |
WB
EL
IHC
FC
OA
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| Novus Biologicals | NB100-64980 |
17 references | Monoclonal |
WB
ICC
IHC
FC
|
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| Proteintech Group | 10593-1-AP |
17 references | Polyclonal |
WB
EL
IHC
|
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| R&D Systems | AF3190 |
1 references | Polyclonal |
WB
ICC
IHC
FC
|
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