AMM03931G

antibody from Leading Biology

Targeting: PPM1B PP2CB, PP2CBETA, PPC2BETAX

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

AMM03931G

Provider

Leading Biology

Product name

PPM1B Antibody (monoclonal) (M01)

Antibody type

Monoclonal

Description

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

1A3-2A4

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.